10 Best Advantage 40 Flea Spot On Treatment For Dogs Cats in The UK

Last updated on 16/07/2025

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FRONTLINE

FRONTLINE Spot On Flea & Tick Treatment for Cats - 6 Pipettes

34% OffFree Shipping

Why We Love It

Ensures 24-hour flea elimination.
Minimizes disease with tick defense.
Promises six-month pet protection.

Main Highlights

KILLS FLEAS - Fleas jumping onto your treated cat are killed within 24 hours, preventing infestations from building up
KILLS TICKS - Helps to reduce the risk of disease transmission by killing ticks that latch onto your treated cat
EASY APPLICATION - Simply empty one pipette onto your cat's skin at the back of the neck and it will quickly spread over their coat - it's as easy as that
TRIED AND TRUSTED - FRONTLINE's original vet-strength formula has an exemplary safety profile and can be used on kittens weighing more than 1 kg, from 8 weeks of age
TREAT MONTHLY - It’s important to treat your pets year-round to prevent flea and tick infestations. One 6-pack provides your cat with 6 months of protection

FRONTLINE Spot On Flea & Tick Treatment for Small Dog (2-10kg) 3 Pipettes

16% OffFree Shipping

Why We Love It

Kills fleas within 24 hours.
Reduces disease transmission risk.
Easy and quick application.

Main Highlights

KILLS FLEAS - Fleas jumping onto your treated dog are killed within 24 hours, preventing infestations from building up
KILLS TICKS - Ticks latching onto your treated dog are killed within 48 hours, helping to reduce the risk of disease transmission
TRIED AND TRUSTED - FRONTLINE's original vet-strength formula has an exemplary safety profile and can be used on puppies weighing more than 2 kg, from 8 weeks of age
EASY APPLICATION - Simply empty one pipette onto your dog's skin at the back of the neck and it will quickly spread over their coat - it's as easy as that
TREAT MONTHLY - It’s important to treat your pets year-round to prevent flea and tick infestations. One 3-pack provides your dog with 3 months of protection

Dog Flea Treatment - Extra Large Dogs x 4 - Spot on Flea Treatment for Dogs XL Very Large Dog 40-60 kg - Flea and Tick Control - Fast Acting FleaSolve Solution - 4 Pipettes

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Why We Love It

Rapid relief guaranteed for dogs.
Hassle-free, quick application.
Year-round protection assured.

Main Highlights

Flea treatment for dogs: Say goodbye to pesky fleas! Our fast-acting spot on flea treatment for dogs provides immediate relief for your furry friend by killing fleas instantly and ticks within 24 - 48 hours using dog flea treatment Extra Large dog.
Tick Off Ticks Too: Flea and tick treatment for dogs! This formula also serves as a dog tick treatment, killing ticks and reducing the risk of disease transmission.
Spot on flea treatment for dogs: Hassle-Free Application. Our spot on tick and flea treatment uses a pipette that is pressed on the back of the dog’s neck to ensure that every drop gets on their coat quickly. Effective XL Dog flea treatment.
No Vet Visit Required: Flea treatment for dogs Large contains fipronil, a strong, vet-strength ingredient, which provides swift relief from infestation and itch without a prescription for dogs.
Large Dog Flea Treatment: Year-Round Protection. With our monthly treatment plan, there's no need to fret about flea or tick seasons. You can enjoy peace of mind knowing your pet is shielded all year long.

Itch | Flea & Tick Spot-On Treatment for Large dogs (20-40kg) | Kills Fleas, Ticks, Lice & Eggs to Prevent Reinfestation | 3 Easy-Apply Pipettes

16% OffFree Shipping

Why We Love It

Kills fleas, ticks, eggs.
Vet-strength double action formula.
Safe for all dogs.

Main Highlights

KILLS FLEAS & TICKS EFFECTIVELY: Each treatment of Itch Flea effectively kills fleas in 24 hours, ticks in 48 hours and protects them for up to a month! Got a flea infestation? Use Itch Flea monthly, alongside Itch Flea Home Spray to tackle the microscopic mingers on your pet and home.
VET STRENGTH FORMULA WITH TWO ACTIVE INGREDIENTS: Fipronil kills live adult fleas, lice and ticks. Unlike cheaper brands, Itch Flea also includes (S) Methoprene. This prevents flea eggs from hatching, larvae from maturing, and immature stages from developing into adult fleas, preventing flea reproduction and massively reducing the chance of a returning infestation.
PREVENTS FLEAS COMING BACK (UNLIKE CHEAPER BRANDS) BY KILLING FLEAS, EGGS & LARVAE TOO: Not all flea treatments are equal. Our double-action formula attacks fleas, flea eggs and larvae, breaking the flea life cycle and preventing fleas coming back. Because, seriously, who wants that?
PROTECT FROM TICKS - Ticks are a threat because they carry serious diseases including Lyme Disease, Babesiosis and Tick-Borne Encephalitis Virus (TBEV) all of which can cause severe health complications for you or your dog. Itch Flea kills ticks. It won’t stop the pests from latching on, but it will kill them within 48 hours – dramatically reducing the chances of them transmitting a nasty infection.
PROTECTION FOR ADULT DOGS AND PUPPIES - Pick the right size for your dog or puppy over 8 weeks old. Contains 3 treatments to be used at monthly intervals as to protect your pet from further flea issues! Itch Flea is safe for all dogs above 2kg, including those who are breeding, pregnant or lactating.

Dog Flea Treatment Large Dog x 6 - Spot on Flea Treatment for Dogs Large 20-40 kg - FleaSolve 6 Pipettes, 6 Doses - Effective Spot-On Treatment

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Why We Love It

Rapid relief from fleas.
Effortless spot-on application.
Vet-strength without prescription.

Main Highlights

Flea treatment for dogs: Say goodbye to pesky fleas! Our fast-acting spot on flea treatment for dogs provides immediate relief for your furry friend by killing fleas instantly and ticks within 24 - 48 hours using dog flea treatment Large dog.
Tick Off Ticks Too: Flea and tick treatment for dogs! This formula also serves as a dog tick treatment, killing ticks and reducing the risk of disease transmission.
Spot on flea treatment for dogs: Hassle-Free Application. Our spot on tick and flea treatment uses a pipette that is pressed on the back of the dog’s neck to ensure that every drop gets on their coat quickly.
No Vet Visit Required: Flea treatment for dogs Large contains fipronil, a strong, vet-strength ingredient, which provides swift relief from infestation and itch without a prescription for dogs.
Large Dog Flea Treatment: Year-Round Protection. With our monthly treatment plan, there's no need to fret about flea or tick seasons. You can enjoy peace of mind knowing your pet is shielded all year long.

Advantage Chewable 56mg Chewable Tablets for Dogs 1.3-2.5kg (3 pack), Flea and Tick Treatment, Fast Acting Kills Fleas Within Hours, Prevention Lasts For A Month, Easy To Administer

Why We Love It

Tasty beef flavor dogs love.
Fast-acting flea elimination guaranteed.
Monthly protection for lasting peace.

Main Highlights

TASTY FLEA & TICK PROTECTION: Use Advantage Chewable Tablets for Dogs to keep your pets protected from fleas and ticks. This beef flavoured chewable tablet is specially formulated for dogs to swiftly eliminate these pesky parasites.
FAST-ACTING FLEA & TICK PROTECTION: If you suspect your dog might be suffering with fleas, take action. The tablet acts rapidly, eradicating existing infestations and preventing new ones, eliminating fleas before they can lay eggs.
PREVENT REINFESTATION: Advantage Chewable Flea Treatment provides your dog with protection that lasts for a whole month. As well as killing fleas that are already on your dog, it continues working for 30 days to prevent reinfestation.
FAST & SIMPLE: Protecting your dog from fleas and ticks is simple. Give them a tasty tablet once a month, no messy treatments - just effective protection that fits seamlessly into your life.
PROTECT YOUR PET: If your pet has fleas, your home has fleas. All of our products are clinically proven to prevent & treat flea infestations to give you peace of mind.

Advantage Spot On Flea Treatment 40 Small Cats Dogs and Rabbits, 4 pipettes

Why We Love It

Effective flea prevention duration.
Convenient single-use pipettes.
Easy monthly application.

Main Highlights

One treatment prevents further flea infestation for up to four weeks on dogs, three to four weeks on cats and up to one week on pet rabbits.
Advantage Flea Treatment is supplied in 1 pack containing 4 single use pipettes
Treatment should be repeated after four weeks

FRONTLINE Spot On Flea & Tick Treatment for Cats - 3 Pipettes

27% OffFree Shipping

Why We Love It

Kills fleas within 24 hours.
Reduces disease transmission risk.
Easy application for quick protection.

Main Highlights

KILLS FLEAS - Fleas jumping onto your treated cat are killed within 24 hours, preventing infestations from building up
KILLS TICKS - Helps to reduce the risk of disease transmission by killing ticks that latch onto your treated cat
EASY APPLICATION - Simply empty one pipette onto your cat's skin at the back of the neck and it will quickly spread over their coat - it's as easy as that
TRIED AND TRUSTED - FRONTLINE's original vet-strength formula has an exemplary safety profile and can be used on kittens weighing more than 1 kg, from 8 weeks of age
TREAT MONTHLY - It’s important to treat your pets year-round to prevent flea and tick infestations. One 3-pack provides your cat with 3 months of protection

Kills fleas and ticks effectively.
Provides monthly continuous protection.
Easy and simple application.

Main Highlights

KILLS FLEAS and TICKS: Beaphar FIPROtec Spot-On for cats is an effective and affordable veterinary medicine to control fleas and ticks on your cat, killing fleas within 24 hours and ticks within 48 hours
MONTHLY TREATMENT: Effective against fleas for up to five weeks. Prevention is the best way to protect your cat from fleas. Treatments can be used monthly for continuous protection
EASY TO APPLY: Simply part the coat between the shoulder blades until the skin is visible. Place the tip of the pipette on the skin and squeeze gently to empty its contents onto the skin. The active formula will then spread across the body and keep your cat protected
SUITABLE FOR CATS and KITTENS: Can be used on cats and kittens from 8 weeks of age weighing more than 1kg
VET STRENGTH TREATMENT: Beaphar FIPROtec Spot-On for cats is a veterinary medicine available without the need for a veterinary prescription. It contains Fipronil which effects the nervous system of fleas, causing hyperactivity. As a result, it is quite common to see 'more' fleas following treatment
DEALING WITH A FLEA INFESTATION: Fleas from pets often infest the animal's basket, bedding and regular resting areas such as carpets and soft furnishings. For best results use with Beaphar FLEAtec Household flea spray to help tackle the infestation in the home

Beaphar - Fiprotec Spot-On for Small Dogs (2-10kg) - Kills Fleas and Ticks - Vet Strength Treatment - 6 Pipettes

31% OffFree Shipping

Why We Love It

Fast-acting flea and tick control.
Monthly treatment for lasting protection.
Easy, stress-free application process.

Main Highlights

KILLS FLEAS AND TICKS: Beaphar FIPROtec Spot-On for Small Dogs is an effective and affordable veterinary medicine to control fleas and ticks on your dog, killing fleas within 24 hours and ticks within 48 hours
MONTHLY TREATMENT: Effective against fleas for up to five weeks. Prevention is the best way to protect your dog from fleas and ticks. Treatment can be used every four weeks
EASY TO APPLY: Simply part the coat between the shoulder blades until the skin is visible. Place the tip of the pipette on the skin and squeeze gently to empty its contents onto the skin. The active formula will then spread across the body and keep your dog protected
SUITABLE FOR DOGS AND PUPPIES: Can be used on dogs and puppies from 8 weeks of age weighing 2-10kg
VET STRENGTH TREATMENT: Beaphar FIPROtec Spot-On for Small Dogs is a veterinary medicine available without the need for a veterinary prescription. It contains fipronil which effects the nervous system of fleas, causing hyperactivity. As a result, it is quite common to see 'more' fleas following treatment
DEALING WITH A FLEA INFESTATION: Fleas from pets often infest the animal's basket, bedding and regular resting areas such as carpets and soft furnishings. For best results, use with Beaphar FLEAtec Household flea spray to help tackle the infestation in the home

8.7

Excellent

Save 31%

We scanned 1364 products

We reviewed these offers relevant to the Advantage 40 Flea Spot On Treatment For Dogs Cats within online retailers such as Amazon, eBay and other local retailers, ensuring we covered all major brands and models. The products we selected come from trusted brands like FRONTLINE, Naqua Ltd, Itch, Advantage, Beaphar, all of which have a reputation for consistently delivering high-quality products that users love and innovative approaches for function & design.

For the best Advantage 40 Flea Spot On Treatment For Dogs Cats in the market, we considered we took a deep dive into 6821 online reviews , focusing on elements like user satisfaction, performance in real-world conditions, and long-term reliability. Our ranking also evaluates each review’s relevancy, authenticity, up-to-dateness and depth so that the comparison is more sound.

We concluded that:

The clear winner of our analysis is FRONTLINE Spot On Flea & Tick Treatment for Cats - 6 Pipettes. We love many things about this product by FRONTLINE. What sets it apart from the competition is Ensures 24-hour flea elimination. , Minimizes disease with tick defense. , Promises six-month pet protection.
The best value product for most shoppers and where user satisfaction is continuously the highest is FRONTLINE Spot On Flea & Tick Treatment for Small Dog (2-10kg) 3 Pipettes by FRONTLINE based on online reviews by bloggers, experts and online shoppers.
The biggest bargain at the moment for Advantage 40 Flea Spot On Treatment For Dogs Cats and the best cost-to-value ratio is FRONTLINE Spot On Flea & Tick Treatment for Cats - 6 Pipettesat FRONTLINE with a 34% discount.
Our list of the best Advantage 40 Flea Spot On Treatment For Dogs Cats is updated regularly to reflect new releases and changes in product availability, so be sure to check back often for the latest rankings and discounts.

10 Best Advantage 40 Flea Spot On Treatment For Dogs Cats in The UK

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We concluded that: