10 Best Dog Flea Treatment Tablets For Large Dogs in The UK

Last updated on 02/08/2025

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Capstar Flea Tablets for Dogs, for Medium and Large Dogs from 11.5kg to 57kg, Oral Medication for Flea Treatment in Dogs, Contains 6x 57mg Nitenpyram Flea Tablet

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Why We Love It

Quickly kills fleas effectively.
Starts working within 30 minutes.
Suitable for large dogs.

Main Highlights

Effective flea treatment: The fast-acting formula ensures quick elimination of fleas, with Capstar flea tablets you can literally see the dead fleas falling off your pet
Fast-acting: Capstar for dogs starts to kill fleas after 30 minutes and eliminates 95% to 100% of adult fleas within just 6 hours
For medium and large dogs: These fast-acting flea tablets feature a 57mg Nitenpyram formula which is suitable for large and medium-sized dogs weighing from 11.5kg up to 57kg
Fuss-free: These dog flea tablets are easy to administer and can be given with or without food. Use one tablet per day until fleas are no longer seen
Fights initial infestations: Capstar is ideal to use as a first line of attack against flea infestations due to its quick speed of kill, ensuring an immediate and effective flea treatment for dogs

Advantage Chewable 225mg Chewable Tablets for Dogs >5.5-11kg (3 pack), Flea and Tick Treatment, Fast Acting Kills Fleas Within Hours, Prevention Lasts For A Month, Easy To Administer

7% Off

Why We Love It

Effective flea and tick control.
Convenient single tasty tablet.
Long-lasting monthly protection.

Main Highlights

TASTY FLEA & TICK PROTECTION: Use Advantage Chewable Tablets for Dogs to keep your pets protected from fleas and ticks. This beef flavoured chewable tablet is specially formulated for dogs to swiftly eliminate these pesky parasites.
FAST-ACTING FLEA & TICK PROTECTION: If you suspect your dog might be suffering with fleas, take action. The tablet acts rapidly, eradicating existing infestations and preventing new ones, eliminating fleas before they can lay eggs.
PREVENT REINFESTATION: Advantage Chewable Flea Treatment provides your dog with protection that lasts for a whole month. As well as killing fleas that are already on your dog, it continues working for 30 days to prevent reinfestation.
FAST & SIMPLE: Protecting your dog from fleas and ticks is simple. Give them a tasty tablet once a month, no messy treatments - just effective protection that fits seamlessly into your life.
PROTECT YOUR PET: If your pet has fleas, your home has fleas. All of our products are clinically proven to prevent & treat flea infestations to give you peace of mind.

Bob Martin Clear Spot On Flea Treatment for Large Dogs (20-40kg) - Kills Fleas & Ticks (3 Pipettes)

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Why We Love It

Effective and speedy flea treatment.
Specially designed for large dogs.
Ensures precise and easy application.

Main Highlights

KILLS FLEAS & TICKS - Effective spot-on treatment, simply apply directly on your dogs skin to kill fleas within 24 hours and ticks within 48 hours.
LARGE DOGS (20-40KG) - Suitable for large dogs over 8 weeks old, weighing between 20-40kg.
HOW TO USE - Simply part your cats fur until the skin is visible, place the tip of the pipette directly against the skin and gently squeeze. Apply half to the base of the back of your dogs head and half between the shoulder blades.
PROTECT YOUR PET - Prevents re-infestation on your pet and in their immediate surroundings. The active ingredient (Fipronil) works quickly to kill fleas & ticks.
LONG TERM PROTECTION - Kills Fleas for up to 8 weeks and kills ticks for up to 4 weeks
PREVENTATIVE CARE IS THE BEST CARE - Contains 3 x spot-on pipettes to be used at monthly intervals as part of an effective and regular flea control program.
MAXIMISE YOUR PROTECTION - Use with Bob Martin Clear Plus Flea Spray for a complete parasite control regime.

FRONTLINE Spot On Flea & Tick Treatment for Large Dog (20-40kg) 3 Pipettes

28% OffFree Shipping

Why We Love It

Kills fleas in 24 hours.
Kills ticks within 48 hours.
Easy monthly application.

Main Highlights

KILLS FLEAS - Fleas jumping onto your treated dog are killed within 24 hours, preventing infestations from building up
KILLS TICKS - Ticks latching onto your treated dog are killed within 48 hours, helping to reduce the risk of disease transmission
TRIED AND TRUSTED - FRONTLINE's original vet-strength formula has an exemplary safety profile
EASY APPLICATION - Simply empty one pipette onto your dog's skin at the back of the neck and it will quickly spread over their coat - it's as easy as that
TREAT MONTHLY - It’s important to treat your pets year-round to prevent flea and tick infestations. One 3-pack provides your dog with 3 months of protection

Beaphar | FIPROtec Spot-On for Large Dogs (20–40kg) | Kills Fleas & Ticks | Vet Strength Treatment | 6 Pipettes

26% OffFree Shipping

Why We Love It

Kills fleas within 24 hours.
Affordable veterinary-grade treatment.
Easy to apply.

Main Highlights

KILLS FLEAS AND TICKS: Beaphar FIPROtec Spot-On for Large Dogs is an effective and affordable veterinary medicine to control fleas and ticks on your dog, killing fleas within 24 hours and ticks within 48 hours.
MONTHLY TREATMENT: Effective against fleas for up to five weeks. Prevention is the best way to protect your dog from fleas and ticks. Treatment can be used every four weeks.
EASY TO APPLY: Simply part the coat between the shoulder blades until the skin is visible. Place the tip of the pipette on the skin and squeeze gently to empty its contents onto the skin. The active formula will then spread across the body and keep your dog protected.
SUITABLE FOR DOGS AND PUPPIES: Can be used on dogs and puppies from 8 weeks of age weighing 20-40kg.
VET STRENGTH TREATMENT: Beaphar FIPROtec Spot-On for Large Dogs is a veterinary medicine available without the need for a veterinary prescription. It contains fipronil which effects the nervous system of fleas, causing hyperactivity. As a result, it is quite common to see 'more' fleas following treatment.
DEALING WITH A FLEA INFESTATION: Fleas from pets often infest the animal's basket, bedding and regular resting areas such as carpets and soft furnishings. For best results, use with Beaphar FLEAtec Household flea spray to help tackle the infestation in the home.

Dog Flea Treatment Large Dog x 2 - Spot on Flea Treatment for Dogs Large 20-40 kg - Fast Acting FleaSolve Solution 2 x Pipettes - 2 x Doses - Effective Spot-On Treatment

41% OffFree Shipping

Why We Love It

Immediate relief for pets.
Ticks and fleas eradicated quickly.
No prescription needed for use.

Main Highlights

Flea treatment for dogs: Say goodbye to pesky fleas! Our fast-acting spot on flea treatment for dogs provides immediate relief for your furry friend by killing fleas instantly and ticks within 24 - 48 hours using dog flea treatment Large dog.
Tick Off Ticks Too: Flea and tick treatment for dogs! This formula also serves as a dog tick treatment, killing ticks and reducing the risk of disease transmission.
Spot on flea treatment for dogs: Hassle-Free Application. Our spot on tick and flea treatment uses a pipette that is pressed on the back of the dog’s neck to ensure that every drop gets on their coat quickly.
No Vet Visit Required: Flea treatment for dogs Large contains fipronil, a strong, vet-strength ingredient, which provides swift relief from infestation and itch without a prescription for dogs.
Large Dog Flea Treatment: Year-Round Protection. With our monthly treatment plan, there's no need to fret about flea or tick seasons. You can enjoy peace of mind knowing your pet is shielded all year long.

Dog Flea Treatment Extra Large Dogs x 2 - Flea Treatment for Dogs XL Very Large Dog 40-60 kg - Spot-On Solution for Fleas and Tick Control - FleaSolve 2 x Pipettes, 2 x Doses

Free Shipping

Why We Love It

Fast-acting relief for dogs.
Easy applicator for stress-free use.
Year-round protection from pests.

Main Highlights

Flea treatment for dogs: Say goodbye to pesky fleas! Our fast-acting spot on flea treatment for dogs provides immediate relief for your furry friend by killing fleas instantly and ticks within 24 - 48 hours using dog flea treatment Extra Large dog.
Tick Off Ticks Too: Flea and tick treatment for dogs! This formula also serves as a dog tick treatment, killing ticks and reducing the risk of disease transmission.
Spot on flea treatment for dogs: Hassle-Free Application. Our spot on tick and flea treatment uses a pipette that is pressed on the back of the dog’s neck to ensure that every drop gets on their coat quickly. Effective XL Dog flea treatment.
No Vet Visit Required: Flea treatment for dogs Large contains fipronil, a strong, vet-strength ingredient, which provides swift relief from infestation and itch without a prescription for dogs.
Large Dog Flea Treatment: Year-Round Protection. With our monthly treatment plan, there's no need to fret about flea or tick seasons. You can enjoy peace of mind knowing your pet is shielded all year long.

Advantage Spot On Flea Treatment For Extra Large Dogs 25 - 40kg (4 pipettes, 400mg), Kills Fleas Within 24 Hours, Prevents Further Infestation For Up To Four Weeks

Why We Love It

Prevents flea infestation effectively.
Easy-to-apply single use.
Lasts for four weeks.

Main Highlights

ADVANTAGE FLEA TREATMENT: Use Spot On Flea Treatment to keep your pets protected from fleas. Advantage spreads quickly across your pet’s skin and coat and is not absorbed into the bloodstream, meaning those pesky parasites do not have to bite to die 1.
FAST-ACTING FLEA PROTECTION: If you suspect your pet might be suffering with fleas, take action. Advantage kills fleas within 24 hours of application, meaning your pet can get back to living a full and happy life.
PREVENT REINFESTATION: For every adult flea that you see, there are many more eggs, larvae and pupae hidden away in carpets, upholstery and bedding. Apply spot on treatment every four weeks to prevent further infestations.
FAST & SIMPLE TO APPLY: Protect your pets from fleas with our easy to apply pipette formulation. Apply one pipette evenly to three to four spots on the top of the back from the shoulder to the base of the tail.
PROTECT YOUR PET, PROTECT YOUR HOME: If your pet has fleas, your home has fleas. Advantage is clinically proven to kill fleas, giving you peace of mind. With Advantage Flea Treatment, fleas are dead, not fed.

Beaphar | FIPROtec Spot-On for Extra Large Dogs (40–60kg) | Kills Fleas & Ticks | Vet Strength Treatment | 4 Pipettes

Free Shipping

Why We Love It

Kills fleas within 24 hours.
Effective for up to month.
Vet strength, easy application.

Main Highlights

KILLS FLEAS AND TICKS: Beaphar FIPROtec Spot-On for Extra Large Dogs is an effective and affordable veterinary medicine to control fleas and ticks on your dog, killing fleas within 24 hours and ticks within 48 hours.
MONTHLY TREATMENT: Effective against fleas for up to five weeks. Prevention is the best way to protect your dog from fleas and ticks. Treatment can be used every four weeks
EASY TO APPLY: Simply part the coat between the shoulder blades until the skin is visible. Place the tip of the pipette on the skin and squeeze gently to empty its contents onto the skin. The active formula will then spread across the body and keep your dog protected
SUITABLE FOR DOGS AND PUPPIES: Can be used on dogs and puppies from 8 weeks of age weighing 40-60kg
VET STRENGTH TREATMENT: Beaphar FIPROtec Spot-On for Extra Large Dogs is a veterinary medicine available without the need for a veterinary prescription. It contains fipronil which effects the nervous system of fleas, causing hyperactivity. As a result, it is quite common to see 'more' fleas following treatment
DEALING WITH A FLEA INFESTATION: Fleas from pets often infest the animal's basket, bedding and regular resting areas such as carpets and soft furnishings. For best results, use with Beaphar FLEAtec Household flea spray to help tackle the infestation in the home

Advantage Spot On Flea Treatment For Large Dogs 10 - 25kg (4 pipettes, 250mg), Kills Fleas Within 24 Hours, Prevents Further Infestation For Up To Four Weeks

Why We Love It

Long-lasting flea protection.
Easy-to-apply treatment.
Convenient monthly usage.

Main Highlights

ADVANTAGE FLEA TREATMENT: Use Spot On Flea Treatment to keep your pets protected from fleas. Advantage spreads quickly across your pet’s skin and coat and is not absorbed into the bloodstream, meaning those pesky parasites do not have to bite to die 1.
FAST-ACTING FLEA PROTECTION: If you suspect your pet might be suffering with fleas, take action. Advantage kills fleas within 24 hours of application, meaning your pet can get back to living a full and happy life.
PREVENT REINFESTATION: For every adult flea that you see, there are many more eggs, larvae and pupae hidden away in carpets, upholstery and bedding. Apply spot on treatment every four weeks to prevent further infestations.
FAST & SIMPLE TO APPLY: Protect your pets from fleas with our easy to apply pipette formulation. Apply one pipette of Advantage Spot On to the skin between the shoulder blades.
PROTECT YOUR PET, PROTECT YOUR HOME: If your pet has fleas, your home has fleas. Advantage is clinically proven to kill fleas, giving you peace of mind. With Advantage Flea Treatment, fleas are dead, not fed.

8.9

Excellent

We scanned 609 products

We reviewed these offers relevant to the Dog Flea Treatment Tablets For Large Dogs within online retailers such as Amazon, eBay and other local retailers, ensuring we covered all major brands and models. The products we selected come from trusted brands like Capstar, Advantage, Bob Martin, FRONTLINE, Beaphar, Naqua Ltd, all of which have a reputation for consistently delivering high-quality products that users love and innovative approaches for function & design.

For the best Dog Flea Treatment Tablets For Large Dogs in the market, we considered we took a deep dive into 3046 online reviews , focusing on elements like user satisfaction, performance in real-world conditions, and long-term reliability. Our ranking also evaluates each review’s relevancy, authenticity, up-to-dateness and depth so that the comparison is more sound.

We concluded that:

The clear winner of our analysis is Capstar Flea Tablets for Dogs, for Medium and Large Dogs from 11.5kg to 57kg, Oral Medication for Flea Treatment in Dogs, Contains 6x 57mg Nitenpyram Flea Tablet. We love many things about this product by Capstar. What sets it apart from the competition is Quickly kills fleas effectively, Starts working within 30 minutes, Suitable for large dogs.
The best value product for most shoppers and where user satisfaction is continuously the highest is Advantage Chewable 225mg Chewable Tablets for Dogs >5.5-11kg (3 pack), Flea and Tick Treatment, Fast Acting Kills Fleas Within Hours, Prevention Lasts For A Month, Easy To Administer by Advantage based on online reviews by bloggers, experts and online shoppers.
The biggest bargain at the moment for Dog Flea Treatment Tablets For Large Dogs and the best cost-to-value ratio is Dog Flea Treatment Large Dog x 2 - Spot on Flea Treatment for Dogs Large 20-40 kg - Fast Acting FleaSolve Solution 2 x Pipettes - 2 x Doses - Effective Spot-On Treatmentat Naqua Ltd with a 41% discount.
Our list of the best Dog Flea Treatment Tablets For Large Dogs is updated regularly to reflect new releases and changes in product availability, so be sure to check back often for the latest rankings and discounts.

10 Best Dog Flea Treatment Tablets For Large Dogs in The UK

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We scanned 609 products

We concluded that: