10 Best Fungal Nail Treatment For Severe Infection in The UK

Last updated on 03/08/2025

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Poderm Pack Duo 2-in-1 Fungal Nail Treatment for Severe Nail Infections | Swiss-Made Serum & Booster | No Filling Needed | FungiGone Nail Fungus Treatment for Damaged Toenails | Podiatrist Developed

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Why We Love It

Combats fungal nail infections effectively.
Accelerates damaged nail regeneration process.
Convenient and user-friendly application.

Main Highlights

𝟐-𝐈𝐍-𝟏 𝐀𝐃𝐕𝐀𝐍𝐂𝐄𝐃 𝐅𝐎𝐑𝐌𝐔𝐋𝐀 𝐂𝐔𝐓𝐒 𝐓𝐑𝐄𝐀𝐓𝐌𝐄𝐍𝐓 𝐓𝐈𝐌𝐄 𝐈𝐍 𝐇𝐀𝐋𝐅: A complete dual-action treatment in one box, featuring the Purifying Oil Serum which forms a protective lipid film over the nail to eliminate fungal infection while rejuvenating the nail, and the Booster Serum which forms a double protective barrier to enhance absorption and accelerate nail regeneration. Together, they work to accelerate nail renewal, cutting the treatment time in half compared to standard applications.
𝐒𝐔𝐏𝐏𝐎𝐑𝐓𝐒 𝐇𝐄𝐀𝐋𝐓𝐇𝐈𝐄𝐑, 𝐂𝐋𝐄𝐀𝐑𝐄𝐑-𝐋𝐎𝐎𝐊𝐈𝐍𝐆 𝐍𝐀𝐈𝐋𝐒: Regular use helps improve the appearance of yellow, thick, brittle and discolored nails. It helps maintain hydration, smooth texture, and overall nail quality while forming a protective layer to support long-term nail health.
𝐄𝐀𝐒𝐘 𝐀𝐏𝐏𝐋𝐈𝐂𝐀𝐓𝐈𝐎𝐍 & 𝐂𝐎𝐌𝐏𝐀𝐓𝐈𝐁𝐋𝐄 𝐖𝐈𝐓𝐇 𝐍𝐀𝐈𝐋 𝐕𝐀𝐑𝐍𝐈𝐒𝐇: Apply the Purifying Oil Serum twice daily on clean, dry nails and the surrounding skin. Use the Booster Serum twice weekly, preferably 5 minutes before applying the Purifying Serum, to optimize absorption. Both come with a precision brush applicator which ensures easy, mess-free application. Fully compatible with Poderm Color Care Nail Varnish for continuous treatment while maintaining a polished appearance.
𝐌𝐄𝐃𝐈𝐂𝐀𝐋-𝐆𝐑𝐀𝐃𝐄, 𝐍𝐀𝐓𝐔𝐑𝐀𝐋 𝐈𝐍𝐆𝐑𝐄𝐃𝐈𝐄𝐍𝐓𝐒: Formulated with 12 ultra-potent antifungal plant extracts, including Tea Tree, Palmarosa, Clove, Macadamia, and Organic Lemon oils, known for their nourishing and protective properties. These ingredients work together to support nail hydration, strength, and overall appearance.
𝐏𝐎𝐃𝐈𝐀𝐓𝐑𝐈𝐒𝐓-𝐃𝐄𝐕𝐄𝐋𝐎𝐏𝐄𝐃 & 𝐒𝐖𝐈𝐒𝐒-𝐌𝐀𝐃𝐄: Poderm is a pioneering leader in professional nail care, developed by expert podiatrists and manufactured under strict Swiss pharmaceutical standards to ensure unparalleled safety, efficacy, and medical-grade quality. Trusted for treating fungal infections, nail psoriasis, eczema, and dyshidrosis. Designed to deliver expert-level care at home.

PODERM – 2-in-1 FUNGAL NAIL INTENSIVE NIGHT TREATMENT Eliminates the fungal infection and renews the nail while you sleep |VEGAN | Professional foot/hand treatment | Quick & Easy | Swiss Made

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Why We Love It

Effective overnight anti-fungal treatment.
Practical, reusable and hygienic.
Natural, organic formulation.

Main Highlights

✅ CONTINUOUSLY ELIMINATES THE FUNGAL INFECTION FOR 8 hours ●● The PODERM FUNGAL NAIL - INTENSIVE NIGHT TREATMENT works while you sleep to continuously combat fungal nails for up to 8 hours while improving the visual appearance of nails that are yellow and damaged from the fungus. Used & developed by podiatrists and dermatologists suitable for adults and diabetics. Medical device.
✅ PATENTED TREATMENT ●● The PODERM FUNGAL NAIL - INTENSIVE NIGHT TREATMENT comprises one PODERM - PURIFIANT Serum and one PODERM Repairing Gel Cap enriched with Tea Tree and Aloe Vera. The PODERM PURIFIANT - Serum effectively combats fungal nails, yellow & damaged nails and nail psoriasis. The PODERM Repairing Gel Cap boosts the overnight repair by keeping the serum in direct contact with the infected nail, thus promoting quicker healing of the fungal infection.
✅ PRACTICAL & HYGIENIC ●● The PODERM repairing gel cap is washable and reusable. It also allows for preventing the risk of contagion and the spread of impurities while you sleep. Apply the Serum to the nail and the healthy skin around it (cuticles, nail bed, folds). Then slide the cap on directly against the skin. Leave to work overnight or for part of the night. Wash the cap with warm soapy water and leave to air dry.
✅ NATURAL AND ORGANIC FORMULATION / SWISS MADE ●● PODERM develops innovative formulations based on biomimetics, using plants that are distilled so as to obtain essential and plant oils that are 100% pure and natural. The manufacture of products in Switzerland includes quality controls compliant with the most exacting standards.
✅ COMPATIBLE WITH THE BOOSTER AND THE PODERM COLOR CARE NAIL VARNISHES. ●● The PODERM – BOOSTER will allow you to halve the nail renewal process time. The PODERM Color Care nail varnishes, available in 17 long-lasting colours, are purifying, nourishing and breathable, allowing the PODERM Serums to pass though in order to continue treating one or more damaged nails. A MEN’S SPECIAL nail varnish is available to camouflage the nail (MAT beige).

Curanail 5% W/V Fungal Nail Treatment Amorolfine Medicated Nail Lacquer once weekly application for fungal nail infection 3ml

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Why We Love It

Effective week-long antifungal treatment.
Waterproof and quick drying.
Can be painted over.

Main Highlights

QUICK-ABSORBING & LONG-TERM: This anti-fungal nail treatment penetrates deep into the nail and combats nail fungus in the entire area; need to apply only once every 7 days and the anti-fungal efficacy prevents infection from spreading
NAIL FUNGAL TREATMENT FOR MILD INFECTION: Suitable for treating infections in the upper half or sides of the finger nail or toe nail; Signs of mild infection include thick or brittle nails that are discoloured
WATERPROOF & FAST DRYING: No loss of effectiveness on contact with water from showering, bathing and swimming; for active lifestyle and holiday travel
PAINTABLE: Can be used under your own nail varnish
Includes 3ml Medicated Nail Lacquer Bottle + 30 x Cleaning Swabs + 30 x Nail Files; ALWAYS READ INSTRUCTION BEFORE USE

PODERM - FUNGAL NAIL TREATMENT - Nail Fungus Treatment for Toenail - Exceptional and Powerful Plants Anti-Fungal Restorative Properties - Professional Foot/Hand Treatment - Quick&Easy - Swiss Made

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Why We Love It

Effectively combats fungal infections.
Clinically proven, high satisfaction.
Easy, quick application process.

Main Highlights

✅ ELIMINATES FUNGAL INFECTIONS AND REJUVENATES THE NAIL ●● The PURIFIANT - FUNGAL NAIL INFECTIONS PODERM oil-serum effectively combats fungal nail infections, damaged & yellowing nails, and nail psoriasis. It has a mechanical action and forms a protective lipid film over the nail, eliminating the fungal infection and wholly rejuvenating the nail. Recommended by podiatrists and dermatologists, suitable for adults, children over 3 years of age, pregnant women, and diabetics. Medical device.
✅ The PODERM PURIFIANT - FUNGAL NAIL INFECTIONS oil-serum has been developed by a Swiss podiatrist to treat the nails of their patients suffering from severe fungal infections, which were difficult to treat with traditional anti-fungal products. Clinically proven treatment: 97% of users found the product to be effective, 73% said that the results were quickly visible, and 100% of users were satisfied with the product.
✅ NATURAL AND ORGANIC FORMULA / SWISS MADE ●● PODERM develops innovative formulas, using the therapeutic properties of plants which are grown using chemical-free processes and then distilled to extract 100% pure and natural essential oils. The product manufacturing process is completed entirely in Switzerland, including quality control protocols which comply with the most demanding standards.
✅ QUICK AND EASY TO USE ●● The bottle comes with an integrated applicator brush. For optimal efficacy, apply the product onto the nail and skin (nail edges, cuticles, nail bed, and grooves). Apply the oil-serum daily, AM and PM, and leave to sink in. For cases of fungal nail infections, PODERM recommends cutting nails regularly and opting for shoes which do not compress your toes and nails.
✅ CAN BE USED WITH PODERM COLOR CARE NAIL VARNISH. ●● PODERM nail varnish is enriched with Tea Tree, Biotin and Silicon. Available in 6 long-lasting colours, boasting purifying, nourishing, and breathable qualities. They keep nails in good health and allow PODERM Oil-Serums pass through in order to continue treating any damaged nails. A SPECIAL MEN'S nail varnish is available to camouflage the nail (MATTE beige).

Emtrix® Fungal Nail Treatment Cream – Extra Strength Nail Fungus Penetrating Formula – Binds Moisture into the Nail – Softens Nourishes & Conditions – No Filing Needed

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Why We Love It

Improves nails in 1 week.
Unique patented, effective formulation.
Dehydrates for healthier nails.

Main Highlights

✅IMPROVES NAIL’S APPEARANCE IN JUST 1 WEEK – Rapidly restores a healthy nail colour by hydrating the nail plate while gently smoothing damaged layers with a gentle peeling effect, smoothing the nail surface. – Thick, damaged or infected toenails / fingernails quickly begin showing a healthier looking colour and sheen.
✅ PATENTED FORMULATION - Based on over 15 years research and development by a team of dermatologists in Sweden. – Emtrix is formulated with a unique patented combination of ingredients which is clinically proven to soften the nail plate, allowing the anti fungal properties of Emtrix to penetrate and perform at their best.
✅ CHANGES THE NAIL’S MICROENVIRONMENT – Fungus can no longer survive. Emtrix improves the nail surface integrity and is clinically proven to have a physical antifungal effect which significantly degrades the cells of the fungi which typically cause onychomycosis (fungal nail infections).
✅ BINDS MOISTURE INTO THE NAIL – A common reason for the nail becoming unsightly, discoloured and deformed is that the nails are to dry. Emtrix increases hydration, creating a stronger and healthier nail surface and quickly improves the appearance of nails.
✅ NO FILING NEEDED – - FREE FROM PRESERVATIVES – SAFE TO USE DURING PREGNANCY – DIABETIC FRIENDLY – FREE FROM PRESERVATIVES – EASY TO USE APPLICATOR – 3 MONTH SUPPLY FOR UP TO 3 NAILS

Scholl 2-in-1 Fungal Nail Treat & Prevent Kit, 3.8ml - Treats the Infection at Source, Fast-Drying Formula, Easy to Use, Clinically Proven Antifungal Treatment for Toenails, 5 Disposable Nail Files

26% OffFree Shipping

Why We Love It

Prevents and treats fungal infection.
Designed for easy, 2-step application.
Shows improvement from two weeks.

Main Highlights

TREATS FUNGAL INFECTION AT THE SOURCE: This clinically proven fungal nail treatment penetrates deep into the nail to target infection directly at its origin, helping restore nail appearance and support healthier-looking toenails over time with regular use
HELPS PREVENT SPREAD AND RECURRENCE: The dual-action formula treats current fungal infections and helps prevent spread to other nails; It also forms a barrier to guard against recurrence, making it ideal for ongoing fungal nail protection
EASY TO USE WITH NO PRESCRIPTION REQUIRED: Simple to apply, the 2-in-1 system includes a brush-on treatment and disposable nail files; The combination of filing and specially formulated ingredients allows for faster penetration at the source of infection
DERMATOLOGICALLY TESTED AND EFFECTIVE: This fungal nail treatment has been dermatologically tested and clinically proven to improve the appearance of infected nails; Improvements can be seen from 2 weeks of use - Always read the instructions
INCLUDES DISPOSABLE FILES FOR HYGIENIC CARE: Five single-use nail files enhance treatment absorption, and help avoid cross-contamination between nails by ensuring each file is used only once on affected areas

Effective for severe nail fungus.
Quick and easy application.
Repair and nourish damaged nails.

Main Highlights

EXCILOR ULTRA FUNGAL NAIL TREATMENT 30ML - Extra strong formula for more extensive fungal nail infections. Delivers complete penetration for up to 24 hours.
VISIBLE IMPROVEMENT FROM DAY 1: Excilor Ultra is formulated to treat advanced fungal nail infections thanks to a revolutionary mode of action. Its extra strong formula creates a hostile environment for the development of fungal nail infection and limits the deterioration of the nail. Its TransActive+ technology allows the product to penetrate completely and continuously for 24 hours to the heart of the nail to reach and stop the spread of the infection. A peelable film forms on the nail for instantly brighter and smoother looking nails.
TREAT & REPAIR: Thanks to its formula enriched with biotin, the damaged nail is deeply nourished and hydrated. These ingredients help repair the damaged nail structure.
EASY AND QUICK TO USE: Excilor Ultra is easily applied with an applicator brush over the entire surface of the nail and under the edge of the nail, once a day. The product penetrates and dries in minutes. An invisible, peelable, water-resistant film is formed. After 24 hours, remove the film and reapply the treatment. No filing required. Suitable for use with nail polish/varnish.

Visible results in 2 weeks.
Formulated for fungal infections.
Promotes stronger, healthier nails.

Main Highlights

VISIBLE RESULTS IN 2 WEEKS: An effective, clinically proven treatment against mild to moderate fungal nail infection. Effective from Day 1* with visibla results from 2 weeks. *In Vitroand in vivo tests.
CLINICALLY PROVEN EFFECTIVENESS: Excilor Solution has been developed specifically to treat fungal nail infections thanks to an effective mode of action. Its formula composed of acetic acid creates a hostile environment for the development of nail fungus and limits the deterioration of the nail.
TRANSACTIVE TECHNOLOGY: Allows the product to penetrate quickly* to the heart of the nail to stop the spread of the nail infection. Once the infection is eradicated, the nail can grow back strong and healthy. *In-vitro experiment.
FORMULA ENRICHED WITH MOISTURISING AGENTS: Thanks to its formula enriched with lipids, glycerol and biotin, the infected nail is deeply nourished and hydrated, allowing the nail to regenerate and grow stronger and healthier.
SIMPLE AND QUICK USE: Excilor Solution 3.3ml is easily applied with an applicator brush over the entire surface of the nail and under the edge of the nail, twice a day (morning and evening).
FOR BEST RESULTS: The product penetrates and dries in seconds. No filing is required. The product is also compatible with nail polish. To obtain the best possible results, it is advisable to treat the infected area for at least 3 months.

Nail Fungus Treatment for Toenail,Fungal Nail Treatment Extra Strong Toenail Fungus Treatment Nail Repair Growth Treatment Nail Softener for Thick Toenails Toe and Finger Nail Solution 30ML (Blue)

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Why We Love It

Visible results in 1-6 weeks.
Radically repairs damaged nails.
Natural ingredients ensure safety.

Main Highlights

【Extra Strong Fungal Nail Treatment 】An effective solution with visible results in just 1-6 weeks. Toenail fungus treatment can reduce infection, penetrate the skin to fix discolored and damaged nails, can gently and effectively in toenails, Nail, Athlete’s foot, and Jock Itch.
【Radically Repair Damaged Nails】This anti fungal nail treatment can radically repair damaged nails,treats cracked, rough nails,discolorations, brittle and split toenails and fingernails.Our formula not only combats nail fungus but also enhances the nail surface, preventing unpleasant odors and future nail problems.
【Safe Formula】This nail fungus treatment for toenail is made exclusively from natural ingredients. It includes Vitis Vinifera Seed Oil, Jojoba Oil, Prunus Amygdalus Dulcis Oil, Argania Spinosa Kernel Oil, Tea tree oil Oil, Vitamin E oil, and Origanum Vulgare Oil,and can fight against discolored and damaged nails powerfully without any discomfort or pain.
【Easy to Use at Home】The fungal nail treatment for toenails are designed as drops for simple application.Just apply toenail drops to the affected toes with the applicator twice a day until the nail can be removed from the groove and trimmed easily, the drops soften and lighten the nails for easy removal at home. We recommend applying the toe nail fungal treatment 2-3 times daily. For best results, it's advisable to leave it on overnight for optimal absorption into the nail.
【Repair & Improve Healthier Nail】Our toenail anti paronychia relief oil with natural ingredient that can softens embedded toenails and corneal tissue, prevents ingrown toenails, simplifies nail cutting and supports healthy nail growth and straightening nails.Our effective relieves toenail pain is safe for your nails and does not cause further irritation. It uses natural ingredients selected for safety and effectiveness for people of all ages.

PODERM - FUNGAL NAIL TREATMENT BOOSTER – extra strong toenail fungus treatment – Fast results – Do not use alone – Swiss made

12% OffFree Shipping

Why We Love It

Speeds up fungal treatment.
Swiss made, organic formula.
Effective and user-approved.

Main Highlights

✅ SPEEDS UP TREATMENT FOR FUNGAL INFECTIONS ●● PODERM The FUNGAL NAIL INFECTION TREATMENT BOOSTER forms a double protective barrier and speeds up the regeneration process for nails that have been yellowed and damaged by fungal nail infections. It halves the treatment time for fungal nail infections. Medical device.
✅ PROFESSIONAL TREATMENT ●● The PODERM DIFFICULT FUNGAL NAIL INFECTION TREATMENT BOOSTER has been developed by a Swiss podiatrist to speed up the treatment of fungal nail infections. Clinically proven treatment: 100% of users found the product to be effective, 75% said that the results were quickly visible, and 100% of users were satisfied with the product.
✅ NOT TO BE USED ALONE ●● PODERM BOOSTER is designed for use alongside the PODERM PURIFIANT - FUNGAL NAIL INFECTION SOLUTION or another daily anti-fungal treatment. Apply the PODERM BOOSTER twice weekly onto the nail, the nail edges, cuticles, nail be and grooves, preferably around 5 minutes before applying PODERM PURIFIANT - FUNGAL NAIL INFECTION or your daily anti-fungal treatment.
✅ NATURAL AND ORGANIC FORMULA / SWISS MADE ●● PODERM develops innovative formulas, using the therapeutic properties of plants which are grown using chemical-free processes and then distilled to extract 100% pure and natural essential oils. The product manufacturing process is completed entirely in Switzerland, including quality control protocols which comply with the most demanding standards.
✅ CAN BE USED WITH PODERM COLOR CARE NAIL VARNISH. ●● PODERM nail varnish is enriched with Tea Tree, Biotin and Silicon. Available in 6 long-lasting colours, boasting purifying, nourishing, and breathable qualities. They keep nails in good health and allow PODERM Oil-Serums pass through in order to continue treating any damaged nails. A SPECIAL MEN'S nail varnish is available to camouflage the nail (MATTE beige).

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We scanned 1114 products

We reviewed these offers relevant to the Fungal Nail Treatment For Severe Infection within online retailers such as Amazon, eBay and other local retailers, ensuring we covered all major brands and models. The products we selected come from trusted brands like PODERM, Curanail, Emtrix, Scholl, Excilor, Boxmom, all of which have a reputation for consistently delivering high-quality products that users love and innovative approaches for function & design.

For the best Fungal Nail Treatment For Severe Infection in the market, we considered we took a deep dive into 5571 online reviews , focusing on elements like user satisfaction, performance in real-world conditions, and long-term reliability. Our ranking also evaluates each review’s relevancy, authenticity, up-to-dateness and depth so that the comparison is more sound.

We concluded that:

The clear winner of our analysis is Poderm Pack Duo 2-in-1 Fungal Nail Treatment for Severe Nail Infections | Swiss-Made Serum & Booster | No Filling Needed | FungiGone Nail Fungus Treatment for Damaged Toenails | Podiatrist Developed. We love many things about this product by PODERM. What sets it apart from the competition is Combats fungal nail infections effectively. , Accelerates damaged nail regeneration process. , Convenient and user-friendly application.
The best value product for most shoppers and where user satisfaction is continuously the highest is PODERM – 2-in-1 FUNGAL NAIL INTENSIVE NIGHT TREATMENT Eliminates the fungal infection and renews the nail while you sleep |VEGAN | Professional foot/hand treatment | Quick & Easy | Swiss Made by PODERM based on online reviews by bloggers, experts and online shoppers.
The biggest bargain at the moment for Fungal Nail Treatment For Severe Infection and the best cost-to-value ratio is Excilor Fungal Nail Infection Treatment | Clinically Proven | Contains Biotin Supporting Repair & A Stronger Nail Barrier Against Fungus | Visible Results In 2 Weeks | No Filing | Fast-Drying | 3.3mlat Excilor with a 34% discount.
Our list of the best Fungal Nail Treatment For Severe Infection is updated regularly to reflect new releases and changes in product availability, so be sure to check back often for the latest rankings and discounts.

10 Best Fungal Nail Treatment For Severe Infection in The UK

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