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Best High Fluoride Toothpaste 5000ppm of 2026
Last updated on 04/04/2026
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1
Gutology Mineral Hydroxyaptite Toothpaste 120ml Microbiome Friendly Fluoride Free Toothpaste Suitable for Adults & Children for Sensitive Teeth - Wild Mint
Gutology
Why we love it
Promotes overall oral health.
Restores lost minerals.
Fluoride-Free protection.
Main Highlights
Biomimetic Hydroxyapatite (We don't use Nano): A fluoride-free mineral that mimics natural enamel. Studied for how it binds to tooth surfaces and supports daily brushing comfort.
Clinically Studied Ingredients: Includes hydroxyapatite, researched in lab and human studies for its interaction with enamel.
Microbiome-Conscious Formula: Formulated with postbiotic technology developed to support microbial balance.
Clean and Family-Friendly: Free from fluoride, SLS, parabens, synthetic foaming agents, and heavy metals. Suitable for adults and children ages 7 and up.
Backed by Ingredient Research: In a 4-week study using 5% hydroxyapatite, participants reported improved brushing comfort over time.
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9.7
Exceptional
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9.7
Exceptional
Gutology
Gutology Mineral Hydroxyaptite Toothpaste 120ml Microbiome Friendly Fluoride Free Toothpaste Suitable for Adults & Children for Sensitive Teeth - Wild Mint
Check Price
Show More
Why we love it
Promotes overall oral health.
Restores lost minerals.
Fluoride-Free protection.
Main Highlights
Biomimetic Hydroxyapatite (We don't use Nano): A fluoride-free mineral that mimics natural enamel. Studied for how it binds to tooth surfaces and supports daily brushing comfort.
Clinically Studied Ingredients: Includes hydroxyapatite, researched in lab and human studies for its interaction with enamel.
Microbiome-Conscious Formula: Formulated with postbiotic technology developed to support microbial balance.
Clean and Family-Friendly: Free from fluoride, SLS, parabens, synthetic foaming agents, and heavy metals. Suitable for adults and children ages 7 and up.
Backed by Ingredient Research: In a 4-week study using 5% hydroxyapatite, participants reported improved brushing comfort over time.
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Value for Money
2
Colgate Sensitive Instant Relief Repair + Gentle Whitening Toothpaste | Instant* and Long-Lasting** Sensitivity Relief | Protective Layer with Calcium** | Fluoride Toothpaste | 4 Pack, 75ml Tubes
Colgate
Why we love it
Blocks sensitivity pain instantly.
Seals and repairs sensitive areas.
Restores natural teeth whiteness.
Main Highlights
FOR INSTANT SENSITIVITY RELIEF*: Our Colgate Sensitive Instant Relief Repair + Gentle Whitening Toothpaste offers instant sensitivity relief* so you can enjoy your favourite food and drinks without hesitation
REPAIRS SENSITIVE AREAS: Our sensitive toothpaste repairs sensitive areas of your teeth** with continued use, ensuring long-lasting comfort and protection
WHITER TEETH: Our fluoride toothpaste helps to restore the natural whiteness of your teeth, giving you a brighter smile
PROTECTIVE LAYER: With calcium, our toothpaste forms a protective layer** that acts like a seal and prevents sensitivity from coming back**
WHITER TEETH: This Colgate whitening toothpaste helps to restore the natural whiteness of your teeth, giving you a brighter smile
INSTANT RELIEF: Colgate Sensitive Instant Relief Toothpaste is designed for sensitive teeth, giving you immediate* and long-lasting** relief
UNIQUE PRO-ARGIN TECHNOLOGY: The unique Pro-Argin technology in our toothpaste plugs the tubules and starts to block sensitivity instantly*
SUITABLE FOR DAILY USE: This Colgate toothpaste multipack is suitable for daily use and provides relief and protection when used as directed
DISCLAIMERS: *For instant relief, apply directly to the sensitive tooth with a fingertip and massage gently for 1 minute up to twice a day, and for children 6-12 years once a week or less frequently. **Repairs sensitive areas of teeth with continued use 2x per day. For lasting relief, apply to a gentle toothbrush, making sure to brush all sensitive areas of teeth
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9.6
Superb
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9.6
Superb
Colgate
Colgate Sensitive Instant Relief Repair + Gentle Whitening Toothpaste | Instant* and Long-Lasting** Sensitivity Relief | Protective Layer with Calcium** | Fluoride Toothpaste | 4 Pack, 75ml Tubes
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Why we love it
Blocks sensitivity pain instantly.
Seals and repairs sensitive areas.
Restores natural teeth whiteness.
Main Highlights
FOR INSTANT SENSITIVITY RELIEF*: Our Colgate Sensitive Instant Relief Repair + Gentle Whitening Toothpaste offers instant sensitivity relief* so you can enjoy your favourite food and drinks without hesitation
REPAIRS SENSITIVE AREAS: Our sensitive toothpaste repairs sensitive areas of your teeth** with continued use, ensuring long-lasting comfort and protection
WHITER TEETH: Our fluoride toothpaste helps to restore the natural whiteness of your teeth, giving you a brighter smile
PROTECTIVE LAYER: With calcium, our toothpaste forms a protective layer** that acts like a seal and prevents sensitivity from coming back**
WHITER TEETH: This Colgate whitening toothpaste helps to restore the natural whiteness of your teeth, giving you a brighter smile
INSTANT RELIEF: Colgate Sensitive Instant Relief Toothpaste is designed for sensitive teeth, giving you immediate* and long-lasting** relief
UNIQUE PRO-ARGIN TECHNOLOGY: The unique Pro-Argin technology in our toothpaste plugs the tubules and starts to block sensitivity instantly*
SUITABLE FOR DAILY USE: This Colgate toothpaste multipack is suitable for daily use and provides relief and protection when used as directed
DISCLAIMERS: *For instant relief, apply directly to the sensitive tooth with a fingertip and massage gently for 1 minute up to twice a day, and for children 6-12 years once a week or less frequently. **Repairs sensitive areas of teeth with continued use 2x per day. For lasting relief, apply to a gentle toothbrush, making sure to brush all sensitive areas of teeth
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3
BIOREPAIR PLUS Sensitive Teeth- Fluoride Free Hydroxyapatite Toothpaste, Reduces Dentin Sensitivity & Pain, Sensitive Toothpaste Adults & Kids, Prevents Enamel Erotion, Oral Care, 75mlx3 Made in Italy
Biorepair
Why we love it
Rapid relief from sensitivity.
Repairs tooth enamel effectively.
Prevents future dental discomfort.
Main Highlights
RAPID RELIEF FOR SENSITIVE TEETH: Biorepair Sensitive Teeth Toothpaste offers quick relief from dental sensitivity and discomfort. Its enhanced formula works from the very first application, providing immediate comfort by reducing dentinal sensitivity and protecting your enamel
LONG LASTING PROTECTION AGAINST SENSITIVITY: Biorepair Plus sensitive teeth forms natural barrier on the tooth surface that seals exposed dentinal tubules, reducing dentin sensitivity and increasing pain relief
IDEAL FOR DAILY USE: Biorepair Plus Sensitive Teeth is gentle enough for daily use, promoting overall oral health. It not only repairs enamel surface and reduces sensitivity but also promotes an overall oral cavity protection
HIGH MICROREPAIR CONCENTRATION: Packed with high levels of microRepair microparticles, this toothpaste uses hydroxyapatite crystals to bond directly to tooth enamel, sealing exposed tubules and helping to repair and strengthen your teeth from the inside out
BIOREPAIR, ADVANCED PROTECTION FOR ORAL HEALTH: Biorepair was created through a partnership between Coswell and the LEBSC at the University of Bologna to revolutionize oral care. It is powerd by microRepair technology, compostion of zinc-hydroxiapatite particles, that mimics tooth enamel to offer unique protection against cavities, erosion, and sensitivity—ensuring strong, healthy teeth every day
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9.4
Superb
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9.4
Superb
Biorepair
BIOREPAIR PLUS Sensitive Teeth- Fluoride Free Hydroxyapatite Toothpaste, Reduces Dentin Sensitivity & Pain, Sensitive Toothpaste Adults & Kids, Prevents Enamel Erotion, Oral Care, 75mlx3 Made in Italy
Check Price
Show More
Why we love it
Rapid relief from sensitivity.
Repairs tooth enamel effectively.
Prevents future dental discomfort.
Main Highlights
RAPID RELIEF FOR SENSITIVE TEETH: Biorepair Sensitive Teeth Toothpaste offers quick relief from dental sensitivity and discomfort. Its enhanced formula works from the very first application, providing immediate comfort by reducing dentinal sensitivity and protecting your enamel
LONG LASTING PROTECTION AGAINST SENSITIVITY: Biorepair Plus sensitive teeth forms natural barrier on the tooth surface that seals exposed dentinal tubules, reducing dentin sensitivity and increasing pain relief
IDEAL FOR DAILY USE: Biorepair Plus Sensitive Teeth is gentle enough for daily use, promoting overall oral health. It not only repairs enamel surface and reduces sensitivity but also promotes an overall oral cavity protection
HIGH MICROREPAIR CONCENTRATION: Packed with high levels of microRepair microparticles, this toothpaste uses hydroxyapatite crystals to bond directly to tooth enamel, sealing exposed tubules and helping to repair and strengthen your teeth from the inside out
BIOREPAIR, ADVANCED PROTECTION FOR ORAL HEALTH: Biorepair was created through a partnership between Coswell and the LEBSC at the University of Bologna to revolutionize oral care. It is powerd by microRepair technology, compostion of zinc-hydroxiapatite particles, that mimics tooth enamel to offer unique protection against cavities, erosion, and sensitivity—ensuring strong, healthy teeth every day
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4
Regenerate Advanced Toothpaste to repair tooth enamel for strong, healthy teeth 75ml
Regenerate
Why we love it
Protects against common tooth problems.
Reverses early enamel erosion.
Boosts tooth enamel regeneration.
Main Highlights
80% of common tooth problems such as sensitivity, transparency and yellowing are caused by enamel erosion and acid attacks
REGENERATE Enamel Science is the first oral care system able to regenerate tooth enamel mineral*, reversing the early enamel erosion process, keeping teeth healthy and strong to future-proof your smile
Its unique NR-5 ingredients combine to form a fresh supply of tooth enamel minerals which wrap and integrate onto teeth
Helps protect against cavities, restore original whiteness and provides 3 times stronger teeth**
Use REGENERATE Advanced Toothpaste twice daily, in place of your regular toothpaste
For best results, use in combination with REGENERATE Advanced Enamel Serum to boost effectiveness by 43%***
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9.2
Superb
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9.2
Superb
Regenerate
Regenerate Advanced Toothpaste to repair tooth enamel for strong, healthy teeth 75ml
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Show More
Why we love it
Protects against common tooth problems.
Reverses early enamel erosion.
Boosts tooth enamel regeneration.
Main Highlights
80% of common tooth problems such as sensitivity, transparency and yellowing are caused by enamel erosion and acid attacks
REGENERATE Enamel Science is the first oral care system able to regenerate tooth enamel mineral*, reversing the early enamel erosion process, keeping teeth healthy and strong to future-proof your smile
Its unique NR-5 ingredients combine to form a fresh supply of tooth enamel minerals which wrap and integrate onto teeth
Helps protect against cavities, restore original whiteness and provides 3 times stronger teeth**
Use REGENERATE Advanced Toothpaste twice daily, in place of your regular toothpaste
For best results, use in combination with REGENERATE Advanced Enamel Serum to boost effectiveness by 43%***
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5
2PCS 9.9% Hydroxyapatite Toothpaste for Enamel Repair and Tooth Strengthening, Nano Hydroxyapatite Remineralizing Toothpaste, Fluoride Free Gentle Whitening Tooth Paste for Sensitive Teeth, Fresh Mint
RoongDuuDll
5% Off
Why we love it
Repairs tooth damage effectively.
Relieves tooth sensitivity significantly.
Prevents cavities with ease.
Main Highlights
REPAIR TEETH DAMAGE - Hydroxyapatite is the main component of tooth enamel, which can effectively fill the tiny cracks on the surface of the teeth and repair tooth damage caused by wear and tear or acid erosion.
RELIEVE TOOTH SENSITIVITY - Our 9.9% nHAP nano hydroxyapatite toothpaste has a higher content, which can effectively seal the dentin tubules and effectively relieve tooth sensitivity caused by external stimuli such as hot, cold, sour and sweet.
PREVENTS CAVITIES - Hydroxyapatite toothpaste remineralizes the surface of the teeth, forming a protective film that strengthens the teeth and reduces cavities.
GENTLE WHITENING - Our restorative toothpaste is fluoride-free, gentle and safe, effectively removing surface stains and restoring the natural whiteness of your teeth.
FRESH BREATH - Hydroxyapatite toothpaste eliminates bad breath by cleaning and soothing teeth. It contains a refreshing mint flavor that provides long-lasting freshness.
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9.1
Superb
Check Price
9.1
Superb
RoongDuuDll
2PCS 9.9% Hydroxyapatite Toothpaste for Enamel Repair and Tooth Strengthening, Nano Hydroxyapatite Remineralizing Toothpaste, Fluoride Free Gentle Whitening Tooth Paste for Sensitive Teeth, Fresh Mint
5% Off
Check Price
Show More
Why we love it
Repairs tooth damage effectively.
Relieves tooth sensitivity significantly.
Prevents cavities with ease.
Main Highlights
REPAIR TEETH DAMAGE - Hydroxyapatite is the main component of tooth enamel, which can effectively fill the tiny cracks on the surface of the teeth and repair tooth damage caused by wear and tear or acid erosion.
RELIEVE TOOTH SENSITIVITY - Our 9.9% nHAP nano hydroxyapatite toothpaste has a higher content, which can effectively seal the dentin tubules and effectively relieve tooth sensitivity caused by external stimuli such as hot, cold, sour and sweet.
PREVENTS CAVITIES - Hydroxyapatite toothpaste remineralizes the surface of the teeth, forming a protective film that strengthens the teeth and reduces cavities.
GENTLE WHITENING - Our restorative toothpaste is fluoride-free, gentle and safe, effectively removing surface stains and restoring the natural whiteness of your teeth.
FRESH BREATH - Hydroxyapatite toothpaste eliminates bad breath by cleaning and soothing teeth. It contains a refreshing mint flavor that provides long-lasting freshness.
Show More
6
Curaprox Perio Plus Support Gel Toothpaste – Oral Care for Gum Issues | Supports Plaque Control and Healing | 75 ml Tube | Designed in Switzerland
Curaprox
5% Off
Why we love it
Chlorhexidine and Hyaluronic Acid enriched.
Flavored with Xylitol.
Alcohol & bleach free.
Main Highlights
Specially formulated with CHX 0.09% and Citrox/P to support gum health and inhibit plaque growth.
Mouthwash-compatible: SLS-free to preserve chlorhexidine's effect and optimise oral care routines.
Enriched with hyaluronic acid to support tissue regeneration after dental treatments.
Natural flavour profile developed with Citrox and expert flavourists for a pleasant brushing experience.
Designed for short-term, dentist-recommended use with a protective film over teeth and gums
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9.0
Superb
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9.0
Superb
Curaprox
Curaprox Perio Plus Support Gel Toothpaste – Oral Care for Gum Issues | Supports Plaque Control and Healing | 75 ml Tube | Designed in Switzerland
5% Off
Check Price
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Why we love it
Chlorhexidine and Hyaluronic Acid enriched.
Flavored with Xylitol.
Alcohol & bleach free.
Main Highlights
Specially formulated with CHX 0.09% and Citrox/P to support gum health and inhibit plaque growth.
Mouthwash-compatible: SLS-free to preserve chlorhexidine's effect and optimise oral care routines.
Enriched with hyaluronic acid to support tissue regeneration after dental treatments.
Natural flavour profile developed with Citrox and expert flavourists for a pleasant brushing experience.
Designed for short-term, dentist-recommended use with a protective film over teeth and gums
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7
Curaprox Enzycal 1450 ppm Toothpaste – Fluoride Toothpaste with Enzymes for Daily Oral Care | Supports Cavity Protection & Fresh Breath | SLS-Free, 75ml | Made in Switzerland
Curaprox
6% Off
Why we love it
Boosts natural saliva protection.
Gentle on the mouth.
Enamel-friendly and protective.
Main Highlights
Supports Strong Teeth: With 1450 ppm fluoride, this daily-use toothpaste helps reinforce enamel and maintain healthy teeth – ideal for long-term oral care.
Gentle, Foam-Free Formula: Free from SLS (sodium lauryl sulfate), making it suitable for those who prefer a mild brushing experience or are prone to oral discomfort.
Enzyme Boost for Mouth Health: Features a unique enzyme system that works with saliva to help manage plaque and support oral hygiene.
Developed in Switzerland: Created under rigorous quality standards, combining innovative dental science with Curaprox’s commitment to gentle care.
Ideal for Daily Use: With medium abrasiveness (RDA 60), it's suitable for those with sensitive teeth, orthodontic needs, or dry mouth.
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8.8
Excellent
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8.8
Excellent
Curaprox
Curaprox Enzycal 1450 ppm Toothpaste – Fluoride Toothpaste with Enzymes for Daily Oral Care | Supports Cavity Protection & Fresh Breath | SLS-Free, 75ml | Made in Switzerland
6% Off
Check Price
Show More
Why we love it
Boosts natural saliva protection.
Gentle on the mouth.
Enamel-friendly and protective.
Main Highlights
Supports Strong Teeth: With 1450 ppm fluoride, this daily-use toothpaste helps reinforce enamel and maintain healthy teeth – ideal for long-term oral care.
Gentle, Foam-Free Formula: Free from SLS (sodium lauryl sulfate), making it suitable for those who prefer a mild brushing experience or are prone to oral discomfort.
Enzyme Boost for Mouth Health: Features a unique enzyme system that works with saliva to help manage plaque and support oral hygiene.
Developed in Switzerland: Created under rigorous quality standards, combining innovative dental science with Curaprox’s commitment to gentle care.
Ideal for Daily Use: With medium abrasiveness (RDA 60), it's suitable for those with sensitive teeth, orthodontic needs, or dry mouth.
Show More
8
Oral-B Clinical Decay Control Intensive Clean Toothpaste 75ml
Oral-B
Why we love it
Reverses calcium loss actively.
Prevents cavities, reduces plaque.
Environmentally friendly packaging.
Main Highlights
Actively reverses calcium loss
Clinically proven anti-plaque and anti-decay ingredient, stannous fluoride, that helps prevent cavities and reduce plaque
Toothpaste with stannous fluoride
Helps prevent cavities and reduce plaque
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8.7
Excellent
Check Price
8.7
Excellent
Oral-B
Oral-B Clinical Decay Control Intensive Clean Toothpaste 75ml
Check Price
Show More
Why we love it
Reverses calcium loss actively.
Prevents cavities, reduces plaque.
Environmentally friendly packaging.
Main Highlights
Actively reverses calcium loss
Clinically proven anti-plaque and anti-decay ingredient, stannous fluoride, that helps prevent cavities and reduce plaque
Toothpaste with stannous fluoride
Helps prevent cavities and reduce plaque
Show More
9
Parodontax Fluoride Toothpaste 75Ml
Parodontax
Why we love it
Contains herbal extracts blend.
Highly effective oral care.
Prevents bleeding and gingivitis.
Main Highlights
Daily Fluoride toothpaste
Unique selection of herbal extracts
Extremely effective combination of minerals and plant extracts
Helps prevent bleeding & gingivitis
75 ml
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8.7
Excellent
Check Price
8.7
Excellent
Parodontax
Parodontax Fluoride Toothpaste 75Ml
Check Price
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Why we love it
Contains herbal extracts blend.
Highly effective oral care.
Prevents bleeding and gingivitis.
Main Highlights
Daily Fluoride toothpaste
Unique selection of herbal extracts
Extremely effective combination of minerals and plant extracts
Helps prevent bleeding & gingivitis
75 ml
Show More
10
9.9% Hydroxyapatite Toothpaste for Enamel Repair and Tooth Strengthening, Nano Hydroxyapatite Remineralizing Toothpaste, Fluoride Free Gentle Whitening Tooth Paste for Sensitive Teeth, Fresh Mint
RoongDuuDll
5% Off
Why we love it
Repairs tooth damage effectively.
Relieves tooth sensitivity fast.
Prevents cavities effectively.
Main Highlights
REPAIR TEETH DAMAGE - Hydroxyapatite is the main component of tooth enamel, which can effectively fill the tiny cracks on the surface of the teeth and repair tooth damage caused by wear and tear or acid erosion.
RELIEVE TOOTH SENSITIVITY - Our 9.9% nHAP nano hydroxyapatite toothpaste has a higher content, which can effectively seal the dentin tubules and effectively relieve tooth sensitivity caused by external stimuli such as hot, cold, sour and sweet.
PREVENTS CAVITIES - Hydroxyapatite toothpaste remineralizes the surface of the teeth, forming a protective film that strengthens the teeth and reduces cavities.
GENTLE WHITENING - Our restorative toothpaste is fluoride-free, gentle and safe, effectively removing surface stains and restoring the natural whiteness of your teeth.
FRESH BREATH - Hydroxyapatite toothpaste eliminates bad breath by cleaning and soothing teeth. It contains a refreshing mint flavor that provides long-lasting freshness.
Show More
8.7
Excellent
Check Price
8.7
Excellent
RoongDuuDll
9.9% Hydroxyapatite Toothpaste for Enamel Repair and Tooth Strengthening, Nano Hydroxyapatite Remineralizing Toothpaste, Fluoride Free Gentle Whitening Tooth Paste for Sensitive Teeth, Fresh Mint
5% Off
Check Price
Show More
Why we love it
Repairs tooth damage effectively.
Relieves tooth sensitivity fast.
Prevents cavities effectively.
Main Highlights
REPAIR TEETH DAMAGE - Hydroxyapatite is the main component of tooth enamel, which can effectively fill the tiny cracks on the surface of the teeth and repair tooth damage caused by wear and tear or acid erosion.
RELIEVE TOOTH SENSITIVITY - Our 9.9% nHAP nano hydroxyapatite toothpaste has a higher content, which can effectively seal the dentin tubules and effectively relieve tooth sensitivity caused by external stimuli such as hot, cold, sour and sweet.
PREVENTS CAVITIES - Hydroxyapatite toothpaste remineralizes the surface of the teeth, forming a protective film that strengthens the teeth and reduces cavities.
GENTLE WHITENING - Our restorative toothpaste is fluoride-free, gentle and safe, effectively removing surface stains and restoring the natural whiteness of your teeth.
FRESH BREATH - Hydroxyapatite toothpaste eliminates bad breath by cleaning and soothing teeth. It contains a refreshing mint flavor that provides long-lasting freshness.
Show More
