We Chose The Best Hydrating Serum For Sensitive Skin in The UK - 10/2025

E45 Face Hydrating Serum - Instant 48-Hour Hyaluronic Acid Formula for Dry, Sensitive & Eczema Prone Skin - Rehydrating & Reinvigorating Serum – Perfume Free - Dermatologically Tested - 30ml

E45 Face Hydrating Serum - Instant 48-Hour Hyaluronic Acid Formula for Dry, Sensitive & Eczema Prone Skin - Rehydrating & Reinvigorating Serum – Perfume Free - Dermatologically Tested - 30ml

E45

33% OffFree Shipping

Why we love it

Boosts moisture instantly.
Gentle on skin.
Easy application process.

Main Highlights

INSTANTLY BOOSTS MOISTURE AND SOOTHES SKIN – Our E45 Hydrating Face Serum gives skin an instant 48-hour hydration boost, whilst helping to restore the skin’s natural barrier. Formulated with a clinically proven triple complex, our serum contains Hyaluronic Acid for intense moisture, microalgae to protect the skin from drying out, and sea water to hold water into the skin. After one application, skin is 55% more hydrated.
KIND-TO-SKIN INGREDIENTS – Gentle and non-greasy, our face serum is dermatologically tested, perfume-free, and vegan. Suitable for dry skin, sensitive skin, and eczema- prone skin, our formulation is quickly absorbed, with a light-weight texture that won’t clog or block pores.
EASY TO APPLY – After cleanser, apply one or two drops of our serum to clean, dry skin. Use twice a day, once in the morning and once in the evening for best results. Our serum can easily slot into your current skincare routine, but we’d recommend this is paired with our E45 Face Foaming Cleanser and E45 Face Daily Protect Moisturiser in the mornings and the E45 Face Night Cream during the evening.
QUALITY SKINCARE EVERY DAY – For more than 70 years, E45 has been a skincare expert in dry and itchy skin and treatment for eczema, psoriasis, ichthyosis, and other dry skin conditions. We understand the importance of quality everyday products that care for your skin with minimal fuss. The E45 range of products has been developed for different skin types and parts of the body and works hard to protect and maintain skin health. Proven dermatological expertise dedicated to vulnerable dry skin.
HISTORY OF E45 – We released our E45 Cream in 1952 after a customer request for a product that would soothe and protect the skin. In 1963 physicians noticed the benefits of E45 cream for dry skin conditions and our cream was introduced to pharmacy and retail in 1980. We’ve continued to create products with individual skin needs in mind. We strive to continue to serve the needs of patients and healthcare professionals and produce better treatment options for patients' skincare routines.

9.0

Superb

9.0

Superb

E45

E45 Face Hydrating Serum - Instant 48-Hour Hyaluronic Acid Formula for Dry, Sensitive & Eczema Prone Skin - Rehydrating & Reinvigorating Serum – Perfume Free - Dermatologically Tested - 30ml

33% OffFree Shipping

Why we love it

Boosts moisture instantly.
Gentle on skin.
Easy application process.

Main Highlights

INSTANTLY BOOSTS MOISTURE AND SOOTHES SKIN – Our E45 Hydrating Face Serum gives skin an instant 48-hour hydration boost, whilst helping to restore the skin’s natural barrier. Formulated with a clinically proven triple complex, our serum contains Hyaluronic Acid for intense moisture, microalgae to protect the skin from drying out, and sea water to hold water into the skin. After one application, skin is 55% more hydrated.
KIND-TO-SKIN INGREDIENTS – Gentle and non-greasy, our face serum is dermatologically tested, perfume-free, and vegan. Suitable for dry skin, sensitive skin, and eczema- prone skin, our formulation is quickly absorbed, with a light-weight texture that won’t clog or block pores.
EASY TO APPLY – After cleanser, apply one or two drops of our serum to clean, dry skin. Use twice a day, once in the morning and once in the evening for best results. Our serum can easily slot into your current skincare routine, but we’d recommend this is paired with our E45 Face Foaming Cleanser and E45 Face Daily Protect Moisturiser in the mornings and the E45 Face Night Cream during the evening.
QUALITY SKINCARE EVERY DAY – For more than 70 years, E45 has been a skincare expert in dry and itchy skin and treatment for eczema, psoriasis, ichthyosis, and other dry skin conditions. We understand the importance of quality everyday products that care for your skin with minimal fuss. The E45 range of products has been developed for different skin types and parts of the body and works hard to protect and maintain skin health. Proven dermatological expertise dedicated to vulnerable dry skin.
HISTORY OF E45 – We released our E45 Cream in 1952 after a customer request for a product that would soothe and protect the skin. In 1963 physicians noticed the benefits of E45 cream for dry skin conditions and our cream was introduced to pharmacy and retail in 1980. We’ve continued to create products with individual skin needs in mind. We strive to continue to serve the needs of patients and healthcare professionals and produce better treatment options for patients' skincare routines.

We scanned 977 products

We reviewed these offers relevant to the Hydrating Serum For Sensitive Skin within online retailers such as Amazon, eBay and other local retailers, ensuring we covered all major brands and models. The products we selected come from trusted brands like Medik8, La Roche-Posay, COSRX, Curel, E45, PURITO, Aveeno, e.l.f., L'Oreal Paris, all of which have a reputation for consistently delivering high-quality products that users love and innovative approaches for function & design.

For the best Hydrating Serum For Sensitive Skin in the market, we considered we took a deep dive into 4886 online reviews , focusing on elements like user satisfaction, performance in real-world conditions, and long-term reliability. Our ranking also evaluates each review’s relevancy, authenticity, up-to-dateness and depth so that the comparison is more sound.

We concluded that:

The clear winner of our analysis is Medik8 Hydr8 B5 - Liquid Rehydration Serum With Hyaluronic Acid - Replenishes, Smooths & Plumps Skin - Ideal For Normal to Sensitive Skin Types - 30ml. We love many things about this product by Medik8. What sets it apart from the competition is Intense hydration with Medik8's formula, Skin retains moisture longer, Boasts lightweight, oil-free formula.

The best value product for most shoppers and where user satisfaction is continuously the highest is La Roche-Posay Toleriane Ultra Dermallergo Hydrating Serum For Sensitive Skin 20ml by La Roche-Posay based on online reviews by bloggers, experts and online shoppers.

The biggest bargain at the moment for Hydrating Serum For Sensitive Skin and the best cost-to-value ratio is PURITO Centella Unscented Serum, Korean Centella, for All Skin Types, Ampoule, Soothing, Calming, Facial Serum for face, Vegan & Cruelty-Free, Korean Skin Care, 60ml 2fl.ozat PURITO with a 37% discount.

Our list of the best Hydrating Serum For Sensitive Skin is updated regularly to reflect new releases and changes in product availability, so be sure to check back often for the latest rankings and discounts.

Best Hydrating Serum For Sensitive Skin of 2025

We scanned 977 products

We concluded that: