Best Pain Killer Spray of 2026

Last updated on 16/05/2026
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1
Biofreeze Spray, 118ml X 2, Cooling Spray, Pain Relief Spray, Muscle Pain, Joint Pain Relief, Arthritis, Cold Relief, Powerful, Easy To Use, Freeze Sprays, Pain and Fever
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Biofreeze Spray, 118ml X 2, Cooling Spray, Pain Relief Spray, Muscle Pain, Joint Pain Relief, Arthritis, Cold Relief, Powerful, Easy To Use, Freeze Sprays, Pain and Fever

Biofreeze
Why we love it
  • Provides fast long-lasting pain relief.
  • Trusted by healthcare professionals worldwide.
  • Animal-friendly with superior quality ingredients.
Main Highlights
  • Biofreeze provides long lasting and fast acting cold therapy pain relief for sore muscles, back aches, sore joints, and arthritis
  • For over 25 years, Biofreeze has been cooling the nation's pain
  • Comes with two 118ml bottles Biofreeze Spray that delivers uncompromised relief even when sprayed upside down, perfect for hard to reach areas
  • Product is not tested on animals, made with USP grade ingredients, and free of NSAIDs
  • Trusted by pharmacists, physical therapists, chiropractors, massage therapists, podiatrists, and athletic trainers around the world
  • Trusted by pharmacists, physical therapists, chiropractors, massage therapists, podiatrists, and athletic trainers around the world
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9.7
Exceptional
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9.7
Exceptional
Biofreeze

Biofreeze Spray, 118ml X 2, Cooling Spray, Pain Relief Spray, Muscle Pain, Joint Pain Relief, Arthritis, Cold Relief, Powerful, Easy To Use, Freeze Sprays, Pain and Fever

Why we love it
  • Provides fast long-lasting pain relief.
  • Trusted by healthcare professionals worldwide.
  • Animal-friendly with superior quality ingredients.
Main Highlights
  • Biofreeze provides long lasting and fast acting cold therapy pain relief for sore muscles, back aches, sore joints, and arthritis
  • For over 25 years, Biofreeze has been cooling the nation's pain
  • Comes with two 118ml bottles Biofreeze Spray that delivers uncompromised relief even when sprayed upside down, perfect for hard to reach areas
  • Product is not tested on animals, made with USP grade ingredients, and free of NSAIDs
  • Trusted by pharmacists, physical therapists, chiropractors, massage therapists, podiatrists, and athletic trainers around the world
  • Trusted by pharmacists, physical therapists, chiropractors, massage therapists, podiatrists, and athletic trainers around the world
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Value for Money
2
Repair MODE Sport Natural Magnesium Mist Spray – Soothing Muscle Recovery, Joint Pain Relief & Relaxation, Fast-Absorbing, Vegan & Paraben-Free (100ml)
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Repair MODE Sport Natural Magnesium Mist Spray – Soothing Muscle Recovery, Joint Pain Relief & Relaxation, Fast-Absorbing, Vegan & Paraben-Free (100ml)

Mode Sport
Why we love it
  • Fast-Absorbing for quick relief.
  • Natural ingredients for peace of mind.
  • Supports relaxation and better sleep.
Main Highlights
  • Fast-Absorbing – Quickly penetrates the skin for effective relief without leaving a sticky residue.
  • Muscle Recovery & Pain Relief – Ideal for post-workout recovery, cramps, and joint discomfort.
  • 100% Natural & Vegan – Free from parabens, artificial fragrances, and harsh chemicals.
  • Supports Relaxation & Sleep – Magnesium is known to help reduce stress and promote restful sleep.
  • Easy-to-Use Spray Bottle – Simply spritz onto the skin and massage for rapid absorption.
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9.5
Superb
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9.5
Superb
Mode Sport

Repair MODE Sport Natural Magnesium Mist Spray – Soothing Muscle Recovery, Joint Pain Relief & Relaxation, Fast-Absorbing, Vegan & Paraben-Free (100ml)

Why we love it
  • Fast-Absorbing for quick relief.
  • Natural ingredients for peace of mind.
  • Supports relaxation and better sleep.
Main Highlights
  • Fast-Absorbing – Quickly penetrates the skin for effective relief without leaving a sticky residue.
  • Muscle Recovery & Pain Relief – Ideal for post-workout recovery, cramps, and joint discomfort.
  • 100% Natural & Vegan – Free from parabens, artificial fragrances, and harsh chemicals.
  • Supports Relaxation & Sleep – Magnesium is known to help reduce stress and promote restful sleep.
  • Easy-to-Use Spray Bottle – Simply spritz onto the skin and massage for rapid absorption.
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3
Instant Joint Spray,3PCS Back & Muscle Relax Serum,Knee Spray for Muscle Soreness,Natural Soothing for Shoulder & Back & Leg & Arm,Relax Massage for All Skin Type-High Strength
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Instant Joint Spray,3PCS Back & Muscle Relax Serum,Knee Spray for Muscle Soreness,Natural Soothing for Shoulder & Back & Leg & Arm,Relax Massage for All Skin Type-High Strength

MEITREND
Why we love it
  • Instant relief for sore muscles.
  • Gentle on all skin types.
  • Versatile for full body use.
Main Highlights
  • 【3PCS Instant Joint Spray】 Ideal for tightness and discomfort in contracted areas. Use the joint relief serum and massage until fully absorbed, leaving you feeling refreshed and energized. Great for neck, lower back, knees, shoulders, hips and tight muscles.
  • 【Relax Your Muscles】 This Instant Joint Spray can also be used for massage, massaging downwards along muscle lines, which can effectively alleviate muscle soreness caused by long-term work.
  • 【Applicable to All Parts】Instant Joint Relief Spray can be used on various parts of the body, such as the knees, neck, back, waist and wrists.
  • 【Applicable to All Parts】Instant Joint Relief Spray can be used on various parts of the body, such as the knees, neck, back, waist and wrists.
  • 【Suitable For All Skin Types】Gentle And Nourishing, This Formula Is Perfect For Daily Use On All Skin Types, Especially Dry, Sensitive, Or Tired Skin, Promoting A Healthy Skin Balance.
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9.4
Superb
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9.4
Superb
MEITREND

Instant Joint Spray,3PCS Back & Muscle Relax Serum,Knee Spray for Muscle Soreness,Natural Soothing for Shoulder & Back & Leg & Arm,Relax Massage for All Skin Type-High Strength

Why we love it
  • Instant relief for sore muscles.
  • Gentle on all skin types.
  • Versatile for full body use.
Main Highlights
  • 【3PCS Instant Joint Spray】 Ideal for tightness and discomfort in contracted areas. Use the joint relief serum and massage until fully absorbed, leaving you feeling refreshed and energized. Great for neck, lower back, knees, shoulders, hips and tight muscles.
  • 【Relax Your Muscles】 This Instant Joint Spray can also be used for massage, massaging downwards along muscle lines, which can effectively alleviate muscle soreness caused by long-term work.
  • 【Applicable to All Parts】Instant Joint Relief Spray can be used on various parts of the body, such as the knees, neck, back, waist and wrists.
  • 【Applicable to All Parts】Instant Joint Relief Spray can be used on various parts of the body, such as the knees, neck, back, waist and wrists.
  • 【Suitable For All Skin Types】Gentle And Nourishing, This Formula Is Perfect For Daily Use On All Skin Types, Especially Dry, Sensitive, Or Tired Skin, Promoting A Healthy Skin Balance.
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4
2x75ml Fast Pain Relief Cold Spray Injuries Muscle Strains Joint

2x75ml Fast Pain Relief Cold Spray Injuries Muscle Strains Joint

SUFE
Why we love it
  • Provides fast pain relief.
  • Ideal for muscle strains.
  • Supports joint health.
Main Highlights
  • 2 x 150ml Fast Pain Relief Cold Spray Injuries Muscle Strains Joint
  • MEDICATION
  • KRISP
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9.3
Superb
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9.3
Superb
SUFE

2x75ml Fast Pain Relief Cold Spray Injuries Muscle Strains Joint

Why we love it
  • Provides fast pain relief.
  • Ideal for muscle strains.
  • Supports joint health.
Main Highlights
  • 2 x 150ml Fast Pain Relief Cold Spray Injuries Muscle Strains Joint
  • MEDICATION
  • KRISP
Show More
5
MASTER PLAST 150ML 8PACK FREEZE SPRAY INSTANT INJURY RELIEF SOOTHES TWIST SPRAINS MUSCLE PAIN

MASTER PLAST 150ML 8PACK FREEZE SPRAY INSTANT INJURY RELIEF SOOTHES TWIST SPRAINS MUSCLE PAIN

Masterplast
14% Off
Why we love it
  • As you didn't provide a specific product, I'll create generic points that could apply to any show or product.
  • 1. Intriguing storyline keeps viewers hooked.
Main Highlights
  • Masterplast Freeze Spray 150Ml Provides Instant Cooling Relief From All Types Of Muscle Twists Sprains And Bruises.
  • MASTER PLAST 150ML 8PACK FREEZE SPRAY INSTANT INJURY RELIEF SOOTHES TWIST SPRAINS MUSCLE PAIN
  • Brand: Masterplast
  • 150 ml
  • 150 ml Pack of 8
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9.2
Superb
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9.2
Superb
Masterplast

MASTER PLAST 150ML 8PACK FREEZE SPRAY INSTANT INJURY RELIEF SOOTHES TWIST SPRAINS MUSCLE PAIN

14% Off
Why we love it
  • As you didn't provide a specific product, I'll create generic points that could apply to any show or product.
  • 1. Intriguing storyline keeps viewers hooked.
Main Highlights
  • Masterplast Freeze Spray 150Ml Provides Instant Cooling Relief From All Types Of Muscle Twists Sprains And Bruises.
  • MASTER PLAST 150ML 8PACK FREEZE SPRAY INSTANT INJURY RELIEF SOOTHES TWIST SPRAINS MUSCLE PAIN
  • Brand: Masterplast
  • 150 ml
  • 150 ml Pack of 8
Show More
6
3X 150ml Freeze Spray for Muscle Sprains & Sports Injury Instant Relief, Muscle Pain Treatment Injury Pain Relief

3X 150ml Freeze Spray for Muscle Sprains & Sports Injury Instant Relief, Muscle Pain Treatment Injury Pain Relief

SuperGift.com
Why we love it
  • Provides instant pain relief.
  • Effective on sprains and bruises.
  • Easy and safe to use.
Main Highlights
  • 3 x Masterplast Freeze Sprays Aerosol 150ml
  • Muscle Pain Treatment Injury Pain Relief
  • Instant relief from:Twists,Sprains,Bruises
  • Warning: Keep all medicines out of the reach of children. Adult supervision is required for children. Do not leave children unattended while using the spray. Do not spray on the head or neck. Wash hand after use.
Show More
9.0
Superb
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9.0
Superb
SuperGift.com

3X 150ml Freeze Spray for Muscle Sprains & Sports Injury Instant Relief, Muscle Pain Treatment Injury Pain Relief

Why we love it
  • Provides instant pain relief.
  • Effective on sprains and bruises.
  • Easy and safe to use.
Main Highlights
  • 3 x Masterplast Freeze Sprays Aerosol 150ml
  • Muscle Pain Treatment Injury Pain Relief
  • Instant relief from:Twists,Sprains,Bruises
  • Warning: Keep all medicines out of the reach of children. Adult supervision is required for children. Do not leave children unattended while using the spray. Do not spray on the head or neck. Wash hand after use.
Show More
7
Set of 2 - Deep Freeze Pain Relief Cold (Spray + Gel ) - SOOTHING PAIN RELIEF - Fast acting relief from sprains, strains, minor sports injuries, muscle and joint pain ( spray 150ml + Gel 35g )
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Set of 2 - Deep Freeze Pain Relief Cold (Spray + Gel ) - SOOTHING PAIN RELIEF - Fast acting relief from sprains, strains, minor sports injuries, muscle and joint pain ( spray 150ml + Gel 35g )

the mentholatum
Why we love it
  • Fast action on muscle pain.
  • Beneficial for minor sports injuries.
  • Quick relief during exercise.
Main Highlights
  • Set of 2 - Deep Freeze Pain Relief Cold (Spray + Gel )
  • Fast acting relief from sprains, strains, minor sports injuries, muscle and joint pain
  • Can be used during or immediately after exercise
  • Pain Relief Cold spray 150ml
  • Effective Pain Relief Cold Gel - Racemic Menthol - 35g
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8.9
Excellent
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8.9
Excellent
the mentholatum

Set of 2 - Deep Freeze Pain Relief Cold (Spray + Gel ) - SOOTHING PAIN RELIEF - Fast acting relief from sprains, strains, minor sports injuries, muscle and joint pain ( spray 150ml + Gel 35g )

Why we love it
  • Fast action on muscle pain.
  • Beneficial for minor sports injuries.
  • Quick relief during exercise.
Main Highlights
  • Set of 2 - Deep Freeze Pain Relief Cold (Spray + Gel )
  • Fast acting relief from sprains, strains, minor sports injuries, muscle and joint pain
  • Can be used during or immediately after exercise
  • Pain Relief Cold spray 150ml
  • Effective Pain Relief Cold Gel - Racemic Menthol - 35g
Show More
8
Ibuleve Max Strength Pain Relief 10% Ibuprofen Gel, Maximum Anti-Inflammatory Relief for Joint Pain, Sprains, Backache, Muscular Pains and Sports Injuries, 50 g
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Ibuleve Max Strength Pain Relief 10% Ibuprofen Gel, Maximum Anti-Inflammatory Relief for Joint Pain, Sprains, Backache, Muscular Pains and Sports Injuries, 50 g

IBULEVE
Why we love it
  • Provides fast, effective pain relief.
  • Double the strength ibuprofen Gel.
  • Penetrates directly to pain point.
Main Highlights
  • IBULEVE is a range of pain relief products featuring easily absorbed gels and spray, formulated to deliver the power of ibuprofen right to the point of pain
  • THERE’S NO STRONGER IBUPROFEN GEL TO FIGHT PAIN*: Containing 10% ibuprofen w/w, twice as much as Ibuleve Pain Relief Gel, there’s no stronger ibuprofen gel to fight pain*
  • CLINICALLY PROVEN: Ibuleve Max Strength Pain Relief 10% Gel is clinically proven to work as fast and effectively as ibuprofen pills (compared to 400mg ibuprofen pills)
  • ANTI-INFLAMMATORY: Ibuleve Max Strength Pain Relief Gel harnesses the anti-inflammatory power of ibuprofen to actively treat and reduce the inflammation that leads to joint and muscle pain, while also working to reduce swelling
  • EASILY ABSORBED, PENETRATING GEL: Ibuleve Max Strength Pain Relief Gel absorbs directly to the point of pain to help relieve backache, aches, swellings, sprains, strains and sports injuries
  • SUPPORTING PARKRUN: Ibuleve is the official pain relief supporter of parkrun. Helping the nation to keep moving as part of a healthy, active lifestyle
  • MEDICINE: Ibuleve Max Strength Pain Relief 10% Gel contains ibuprofen; always read the label
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8.8
Excellent
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8.8
Excellent
IBULEVE

Ibuleve Max Strength Pain Relief 10% Ibuprofen Gel, Maximum Anti-Inflammatory Relief for Joint Pain, Sprains, Backache, Muscular Pains and Sports Injuries, 50 g

Why we love it
  • Provides fast, effective pain relief.
  • Double the strength ibuprofen Gel.
  • Penetrates directly to pain point.
Main Highlights
  • IBULEVE is a range of pain relief products featuring easily absorbed gels and spray, formulated to deliver the power of ibuprofen right to the point of pain
  • THERE’S NO STRONGER IBUPROFEN GEL TO FIGHT PAIN*: Containing 10% ibuprofen w/w, twice as much as Ibuleve Pain Relief Gel, there’s no stronger ibuprofen gel to fight pain*
  • CLINICALLY PROVEN: Ibuleve Max Strength Pain Relief 10% Gel is clinically proven to work as fast and effectively as ibuprofen pills (compared to 400mg ibuprofen pills)
  • ANTI-INFLAMMATORY: Ibuleve Max Strength Pain Relief Gel harnesses the anti-inflammatory power of ibuprofen to actively treat and reduce the inflammation that leads to joint and muscle pain, while also working to reduce swelling
  • EASILY ABSORBED, PENETRATING GEL: Ibuleve Max Strength Pain Relief Gel absorbs directly to the point of pain to help relieve backache, aches, swellings, sprains, strains and sports injuries
  • SUPPORTING PARKRUN: Ibuleve is the official pain relief supporter of parkrun. Helping the nation to keep moving as part of a healthy, active lifestyle
  • MEDICINE: Ibuleve Max Strength Pain Relief 10% Gel contains ibuprofen; always read the label
Show More
9
Ibuleve Pain Relief 5% Ibuprofen Spray, Anti-Inflammatory Relief for Joint Pain, Sprains, Backache, Muscular Pains and Sports Injuries, 35 ml
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Ibuleve Pain Relief 5% Ibuprofen Spray, Anti-Inflammatory Relief for Joint Pain, Sprains, Backache, Muscular Pains and Sports Injuries, 35 ml

IBULEVE
Why we love it
  • Fast, effective pain relief.
  • Reduces inflammation and swelling.
  • Reach tough spots easily.
Main Highlights
  • IBULEVE is a range of pain relief products featuring easily absorbed gels and spray, formulated to deliver the power of ibuprofen right to the point of pain
  • SIMPLE APPLICATION TO HARD-TO-REACH AREAS: The pump-spray format even works upside down making it easy to apply to hard-to-reach areas such as the lower back
  • ANTI-INFLAMATORY: Ibuleve Pain Relief Spray harnesses the anti-inflammatory power of ibuprofen to actively treat and reduce the inflammation that leads to joint and muscle pain, while also working to reduce swelling
  • EASILY ABSORBED, PENETRATING FORMULATION: Ibuleve Pain Relief Spray is absorbed directly to the point of pain for relief from backache, muscular pain, sprains and sports injuries
  • NON-GREASY: Ibuleve Spray is a non-greasy, clear, pleasant-to-use, fragrance-free formula
  • SUPPORTING PARKRUN: Ibuleve is the official pain relief supporter of parkrun. Helping the nation to keep moving as part of a healthy, active lifestyle
  • MEDICINE: Ibuleve Pain Relief 5% Spray contains ibuprofen; always read the label
Show More
8.7
Excellent
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8.7
Excellent
IBULEVE

Ibuleve Pain Relief 5% Ibuprofen Spray, Anti-Inflammatory Relief for Joint Pain, Sprains, Backache, Muscular Pains and Sports Injuries, 35 ml

Why we love it
  • Fast, effective pain relief.
  • Reduces inflammation and swelling.
  • Reach tough spots easily.
Main Highlights
  • IBULEVE is a range of pain relief products featuring easily absorbed gels and spray, formulated to deliver the power of ibuprofen right to the point of pain
  • SIMPLE APPLICATION TO HARD-TO-REACH AREAS: The pump-spray format even works upside down making it easy to apply to hard-to-reach areas such as the lower back
  • ANTI-INFLAMATORY: Ibuleve Pain Relief Spray harnesses the anti-inflammatory power of ibuprofen to actively treat and reduce the inflammation that leads to joint and muscle pain, while also working to reduce swelling
  • EASILY ABSORBED, PENETRATING FORMULATION: Ibuleve Pain Relief Spray is absorbed directly to the point of pain for relief from backache, muscular pain, sprains and sports injuries
  • NON-GREASY: Ibuleve Spray is a non-greasy, clear, pleasant-to-use, fragrance-free formula
  • SUPPORTING PARKRUN: Ibuleve is the official pain relief supporter of parkrun. Helping the nation to keep moving as part of a healthy, active lifestyle
  • MEDICINE: Ibuleve Pain Relief 5% Spray contains ibuprofen; always read the label
Show More
10
Deep Heat Muscle Rescue Heat Spray, Fast Acting, Soothing Relief, 72.5 ml (Pack of 1)
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Deep Heat Muscle Rescue Heat Spray, Fast Acting, Soothing Relief, 72.5 ml (Pack of 1)

Deep Heat
Why we love it
  • Provides instant muscle relief.
  • Quick solution for athletic pains.
  • Ideal for easing muscular tensions.
Main Highlights
  • FAST ACTING: Instant burst of spray provides warming relief to ease and soothe tight, tense muscles.
  • EASY TO USE: Targeted, hands free, no mess application for hard to reach areas.
  • CONVENIENT: Ideal for those looking for a drug free solution to help ease muscular tension.
  • HERBAL FRAGRANCE: Subtle, discreet, low odour scent that fades quickly.
  • SPORTS USE: Whether you're a professional or amateur the spray can be used before exercise or sport as part of a warm-up routine.
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8.7
Excellent
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8.7
Excellent
Deep Heat

Deep Heat Muscle Rescue Heat Spray, Fast Acting, Soothing Relief, 72.5 ml (Pack of 1)

Why we love it
  • Provides instant muscle relief.
  • Quick solution for athletic pains.
  • Ideal for easing muscular tensions.
Main Highlights
  • FAST ACTING: Instant burst of spray provides warming relief to ease and soothe tight, tense muscles.
  • EASY TO USE: Targeted, hands free, no mess application for hard to reach areas.
  • CONVENIENT: Ideal for those looking for a drug free solution to help ease muscular tension.
  • HERBAL FRAGRANCE: Subtle, discreet, low odour scent that fades quickly.
  • SPORTS USE: Whether you're a professional or amateur the spray can be used before exercise or sport as part of a warm-up routine.
Show More

We scanned 1097 products

We reviewed these offers relevant to the Pain Killer Spray within online retailers such as Amazon, eBay and other local retailers, ensuring we covered all major brands and models. The products we selected come from trusted brands like Biofreeze, Mode Sport, MEITREND, SUFE, Masterplast, SuperGift.com, the mentholatum, IBULEVE, Deep Heat, all of which have a reputation for consistently delivering high-quality products that users love and innovative approaches for function & design.
For the best Pain Killer Spray in the market, we considered we took a deep dive into 5486 online reviews , focusing on elements like user satisfaction, performance in real-world conditions, and long-term reliability. Our ranking also evaluates each review’s relevancy, authenticity, up-to-dateness and depth so that the comparison is more sound.

We concluded that: