We Chose The Best Pain Killers in The UK - 10/2025

Combogesic Pain Relief Paracetamol 500 mg and Ibuprofen 150 mg, for Headache, Migraine Relief, Period, Toothache and Back Pain, Cold and Flu Symptoms, Painkillers, Pack of 16 Tablets

Combogesic Pain Relief Paracetamol 500 mg and Ibuprofen 150 mg, for Headache, Migraine Relief, Period, Toothache and Back Pain, Cold and Flu Symptoms, Painkillers, Pack of 16 Tablets

Combogesic

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Why we love it

Unique, patented formulation for relief.
Faster, stronger pain alleviation.
Effective for diverse pain symptoms.

Main Highlights

This product is QUANTITY RESTRICTED and a maximum of 2 products containing paracetamol, aspirin or ibuprofen can be bought per week per customer
WORLD-FIRST specific combination analgesic that combines paracetamol 500 mg and ibuprofen 150 mg in a unique, patented formulation, for temporary relief of mild to moderate pain which has not been relieved by paracetamol or ibuprofen individually
FASTER, STRONGER pain relief than paracetamol or ibuprofen tablets alone, clinically proven to be: 80 percent more effective than paracetamol alone and 30 percent more effective than ibuprofen alone, faster onset of meaningful pain relief than paracetamol or ibuprofen alone
PROVIDES FAST AND EFFECTIVE double action pain relief for a wide range of acute pain symptoms such as headache, migraine headache, tension headache, muscular pain, back pain, period pain, toothache pain, fever, aches and pain from cold and flu, sinus pain, sore throat
DIFFERENT TO OTHER paracetamol/ibuprofen combinations: The daily dose for Combogesic is 1-2 tablets every 6 hours (up to max. 6 tablets), this box of Combogesic Pain Relief contains 16 tablets
Combogesic Pain Relief Tablets, for pain not relieved by paracetamol or ibuprofen individually, always read the label

9.0

Superb

9.0

Superb

Combogesic

Combogesic Pain Relief Paracetamol 500 mg and Ibuprofen 150 mg, for Headache, Migraine Relief, Period, Toothache and Back Pain, Cold and Flu Symptoms, Painkillers, Pack of 16 Tablets

Free Shipping

Why we love it

Unique, patented formulation for relief.
Faster, stronger pain alleviation.
Effective for diverse pain symptoms.

Main Highlights

This product is QUANTITY RESTRICTED and a maximum of 2 products containing paracetamol, aspirin or ibuprofen can be bought per week per customer
WORLD-FIRST specific combination analgesic that combines paracetamol 500 mg and ibuprofen 150 mg in a unique, patented formulation, for temporary relief of mild to moderate pain which has not been relieved by paracetamol or ibuprofen individually
FASTER, STRONGER pain relief than paracetamol or ibuprofen tablets alone, clinically proven to be: 80 percent more effective than paracetamol alone and 30 percent more effective than ibuprofen alone, faster onset of meaningful pain relief than paracetamol or ibuprofen alone
PROVIDES FAST AND EFFECTIVE double action pain relief for a wide range of acute pain symptoms such as headache, migraine headache, tension headache, muscular pain, back pain, period pain, toothache pain, fever, aches and pain from cold and flu, sinus pain, sore throat
DIFFERENT TO OTHER paracetamol/ibuprofen combinations: The daily dose for Combogesic is 1-2 tablets every 6 hours (up to max. 6 tablets), this box of Combogesic Pain Relief contains 16 tablets
Combogesic Pain Relief Tablets, for pain not relieved by paracetamol or ibuprofen individually, always read the label

We scanned 777 products

We reviewed these offers relevant to the Pain Killers within online retailers such as Amazon, eBay and other local retailers, ensuring we covered all major brands and models. The products we selected come from trusted brands like Diohespan Max, Flarin, Voltarol, Nurofen, Panadol, Combogesic, all of which have a reputation for consistently delivering high-quality products that users love and innovative approaches for function & design.

For the best Pain Killers in the market, we considered we took a deep dive into 3886 online reviews , focusing on elements like user satisfaction, performance in real-world conditions, and long-term reliability. Our ranking also evaluates each review’s relevancy, authenticity, up-to-dateness and depth so that the comparison is more sound.

We concluded that:

The clear winner of our analysis is DIOHESPAN MAX 60 Tablets - 1000mg - Swelling Legs Pain Cramps Relief - Spider Varicose Veins Relief. We love many things about this product by Diohespan Max. What sets it apart from the competition is Promotes leg cramp relief, Reduces varicose vein discomfort, Alleviates leg swelling effectively.

The best value product for most shoppers and where user satisfaction is continuously the highest is Flarin Joint and Muscular Pain Relief, 200 mg Soft Capsules, Muscle, Rheumatic, Joint and Back Pain Relief, Lipid Ibuprofen, Unique Lipid Formulation, Painkillers, 16 Soft Capsules by Flarin based on online reviews by bloggers, experts and online shoppers.

The biggest bargain at the moment for Pain Killers and the best cost-to-value ratio is Nurofen Express Ibuprofen Liquid Capsules 200mg, 16 Count - Fast-Acting Relief for Period Pain, Headaches, Migraines, Cold & Flu Symptomsat Nurofen with a 32% discount.

Our list of the best Pain Killers is updated regularly to reflect new releases and changes in product availability, so be sure to check back often for the latest rankings and discounts.

Best Pain Killers of 2025

We scanned 777 products

We concluded that: