Best Spot Treatment Gel of 2025

Last updated on 18/09/2025
Advertising disclosure
Advertising disclosure
Most Relevant
Most Relevant
Best Choice
1
ICF | Clorexyderm Spot Gel | Advanced Cat & Dog Skin Care Gel for Itchy Skin & Wound Relief | Soothes and Moisturizes Irritated Skin | Ideal for Paws, Skin Folds, and Localized Issues
ICF | Clorexyderm Spot Gel | Advanced Cat & Dog Skin Care Gel for Itchy Skin & Wound Relief | Soothes and Moisturizes Irritated Skin | Ideal for Paws, Skin Folds, and Localized Issues
ICF
Free Shipping
Why we love it
  • Soothes and rebalances skin.
  • Offers enhanced skin protection.
  • Versatile and gentle application.
Main Highlights
  • Advanced Pet Skin Gel: Easy-to-use formula designed for dogs and cats, effectively tackling localized skin problems caused by bacteria and yeast.
  • Soothes and Rebalances: Antibacterial and Antifungal properties help soothe red, itchy, and irritated skin, while rebalancing the skin microflora.
  • Enhanced Protection: Forms a protective layer on the skin surface, minimizing contamination from licking and other irritants.
  • Gentle and Odorless: Non-irritating, non-stinging formula with no unpleasant odor, ensuring a comfortable application for your furry companions.
  • Versatile Application: Ideal for paws, skin folds, lip folds, facial folds, ear pinna, and other specific skin areas. Restore skin health by applying 1-2 times a day for 7-14 days.
Show More
9.8
Exceptional
9.8
Exceptional
ICF
ICF | Clorexyderm Spot Gel | Advanced Cat & Dog Skin Care Gel for Itchy Skin & Wound Relief | Soothes and Moisturizes Irritated Skin | Ideal for Paws, Skin Folds, and Localized Issues
Free Shipping
Why we love it
  • Soothes and rebalances skin.
  • Offers enhanced skin protection.
  • Versatile and gentle application.
Main Highlights
  • Advanced Pet Skin Gel: Easy-to-use formula designed for dogs and cats, effectively tackling localized skin problems caused by bacteria and yeast.
  • Soothes and Rebalances: Antibacterial and Antifungal properties help soothe red, itchy, and irritated skin, while rebalancing the skin microflora.
  • Enhanced Protection: Forms a protective layer on the skin surface, minimizing contamination from licking and other irritants.
  • Gentle and Odorless: Non-irritating, non-stinging formula with no unpleasant odor, ensuring a comfortable application for your furry companions.
  • Versatile Application: Ideal for paws, skin folds, lip folds, facial folds, ear pinna, and other specific skin areas. Restore skin health by applying 1-2 times a day for 7-14 days.
Show More
Value for Money
2
CeraVe Blemish Control Gel Moisturiser with 2% Salicylic Acid & Niacinamide for Blemish-Prone Skin 40ml
CeraVe Blemish Control Gel Moisturiser with 2% Salicylic Acid & Niacinamide for Blemish-Prone Skin 40ml
CeraVe
25% OffFree Shipping
Why we love it
  • Developed by dermatology experts.
  • Long-lasting, moisturizing effects.
  • Ideal for blemish-prone skin.
Main Highlights
  • Developed with Dermatologists.
  • Contains 3 Essential Ceramides to help protect the skin's natural barrier.
  • Lightweight gel moisturiser that works to penetrate pores to eliminate the cause of spots & blemishes.
  • Formulated with MVE Technology to lock in moisture, providing 24-hour hydration.
  • Gentle on skin. Suitable for blemish-prone skin.
  • CeraVe is recommended by 99% of UK Dermatologists (*Survey conducted on 101 Dermatologists in the UK, July 2024.)
Show More
9.6
Superb
9.6
Superb
CeraVe
CeraVe Blemish Control Gel Moisturiser with 2% Salicylic Acid & Niacinamide for Blemish-Prone Skin 40ml
25% OffFree Shipping
Why we love it
  • Developed by dermatology experts.
  • Long-lasting, moisturizing effects.
  • Ideal for blemish-prone skin.
Main Highlights
  • Developed with Dermatologists.
  • Contains 3 Essential Ceramides to help protect the skin's natural barrier.
  • Lightweight gel moisturiser that works to penetrate pores to eliminate the cause of spots & blemishes.
  • Formulated with MVE Technology to lock in moisture, providing 24-hour hydration.
  • Gentle on skin. Suitable for blemish-prone skin.
  • CeraVe is recommended by 99% of UK Dermatologists (*Survey conducted on 101 Dermatologists in the UK, July 2024.)
Show More
3
Anicura Natural Dog Gel Ointment for dry & itchy skin, hot spots, eczema & skin allergies
Anicura Natural Dog Gel Ointment for dry & itchy skin, hot spots, eczema & skin allergies
Anicura
Free Shipping
Why we love it
  • Omega-rich hydration for skin.
  • Protects against environmental irritants.
  • Safe for pets if ingested.
Main Highlights
  • SOOTHES AND RESTORES DAMAGED SKIN – Specially designed to calm dry, irritated, and inflamed skin, as well as rashes, scabs, cuts, grazes, small wounds, and sores.
  • COOLS AND RELIEVES DISCOMFORT – The gel’s cooling texture reduces irritation, discouraging scratching, licking, or rubbing, allowing the skin to heal.
  • HYDRATES AND PROTECTS – Omega-rich formula deeply moisturises and forms a soft layer over the skin to lock in moisture and provide lasting protection.
  • BOOSTS SKIN RECOVERY – Infused with antibacterial Apple Cider Vinegar and nutrient-rich Sea Buckthorn to reduce inflammation and support skin healing.
  • EASY TO APPLY ON SENSITIVE AREAS – Gentle enough for use on delicate areas like the face and paw pads, offering quick and hassle-free application.
  • SAFE IF INGESTED – Non-toxic formula provides peace of mind in case your dog licks the treated area.
  • BEST RESULTS WITH COMPANION PRODUCTS – For optimal care, use alongside Anicura Dog Spray and Dog Shampoo.
Show More
9.5
Superb
9.5
Superb
Anicura
Anicura Natural Dog Gel Ointment for dry & itchy skin, hot spots, eczema & skin allergies
Free Shipping
Why we love it
  • Omega-rich hydration for skin.
  • Protects against environmental irritants.
  • Safe for pets if ingested.
Main Highlights
  • SOOTHES AND RESTORES DAMAGED SKIN – Specially designed to calm dry, irritated, and inflamed skin, as well as rashes, scabs, cuts, grazes, small wounds, and sores.
  • COOLS AND RELIEVES DISCOMFORT – The gel’s cooling texture reduces irritation, discouraging scratching, licking, or rubbing, allowing the skin to heal.
  • HYDRATES AND PROTECTS – Omega-rich formula deeply moisturises and forms a soft layer over the skin to lock in moisture and provide lasting protection.
  • BOOSTS SKIN RECOVERY – Infused with antibacterial Apple Cider Vinegar and nutrient-rich Sea Buckthorn to reduce inflammation and support skin healing.
  • EASY TO APPLY ON SENSITIVE AREAS – Gentle enough for use on delicate areas like the face and paw pads, offering quick and hassle-free application.
  • SAFE IF INGESTED – Non-toxic formula provides peace of mind in case your dog licks the treated area.
  • BEST RESULTS WITH COMPANION PRODUCTS – For optimal care, use alongside Anicura Dog Spray and Dog Shampoo.
Show More
4
LANBENA Precision Acne Treatment Spot Serum, Drying Lotion, Overnight Acne Treatment For Face, Dry Out Pimples, Blemishes, Zits And Clean Pores, 0.42 Fl Oz (Pack of 1)
LANBENA Precision Acne Treatment Spot Serum, Drying Lotion, Overnight Acne Treatment For Face, Dry Out Pimples, Blemishes, Zits And Clean Pores, 0.42 Fl Oz (Pack of 1)
LANBENA
Free Shipping
Why we love it
  • Rapidly reduces pimple size.
  • Gentle on sensitive skin.
  • Works overnight while you sleep.
Main Highlights
  • GET DESIRED RESULT FAST – LANBENA Drying Lotion rapidly reduces the severity and the size of pimples overnight while you sleep. It also minimizes the risk of acne scars and keeps skin smooth and blemish-free!
  • TARGETS CYSTIC ACNE, BLEMISHES & PIMPLES – This acne spot serum reduces the severity and the size of pimples and unblocks blocked pores by dissolving debris and oil buildup, stopping the cause of acne by essentially cleaning in your skin.
  • SAFE FOR SENSITIVE SKIN– Gentle to use on delicate, acne-prone skin, but fast and effective in treating infection, healing of current breakouts while preventing new ones from forming! This does not contain harmful ingredients that can cause skin irritation.
  • WORKS OVERNIGHT WHILE YOU SLEEP – Our drying lotion is applied on before going to bed, and the lotion will work on undoing your acne while you sleep. Gently targets breakouts anywhere on your face, exfoliates the skin, and smooth irritated areas for instant results just days after application!
  • CRUELTY-FREE & VEGAN-FRIENDLY- This fast-acting acne eliminator has a veggie-based scent and safe for everyone to use. It is 100 % cruelty-free, never tested on animals. Hypoallergenic, Paraben-Free, Sulfate-Free.
Show More
9.4
Superb
9.4
Superb
LANBENA
LANBENA Precision Acne Treatment Spot Serum, Drying Lotion, Overnight Acne Treatment For Face, Dry Out Pimples, Blemishes, Zits And Clean Pores, 0.42 Fl Oz (Pack of 1)
Free Shipping
Why we love it
  • Rapidly reduces pimple size.
  • Gentle on sensitive skin.
  • Works overnight while you sleep.
Main Highlights
  • GET DESIRED RESULT FAST – LANBENA Drying Lotion rapidly reduces the severity and the size of pimples overnight while you sleep. It also minimizes the risk of acne scars and keeps skin smooth and blemish-free!
  • TARGETS CYSTIC ACNE, BLEMISHES & PIMPLES – This acne spot serum reduces the severity and the size of pimples and unblocks blocked pores by dissolving debris and oil buildup, stopping the cause of acne by essentially cleaning in your skin.
  • SAFE FOR SENSITIVE SKIN– Gentle to use on delicate, acne-prone skin, but fast and effective in treating infection, healing of current breakouts while preventing new ones from forming! This does not contain harmful ingredients that can cause skin irritation.
  • WORKS OVERNIGHT WHILE YOU SLEEP – Our drying lotion is applied on before going to bed, and the lotion will work on undoing your acne while you sleep. Gently targets breakouts anywhere on your face, exfoliates the skin, and smooth irritated areas for instant results just days after application!
  • CRUELTY-FREE & VEGAN-FRIENDLY- This fast-acting acne eliminator has a veggie-based scent and safe for everyone to use. It is 100 % cruelty-free, never tested on animals. Hypoallergenic, Paraben-Free, Sulfate-Free.
Show More
5
Origins Super Spot Remover Blemish Treatment Gel White
Origins Super Spot Remover Blemish Treatment Gel White
Origins
41% OffFree Shipping
Why we love it
  • Hydrates and soothes skin.
  • Convenient and effortless application.
  • Top-notch and luxurious formula.
Main Highlights
  • Skin moisturizer
  • Easy to use
  • Premium quality
Show More
9.4
Superb
9.4
Superb
Origins
Origins Super Spot Remover Blemish Treatment Gel White
41% OffFree Shipping
Why we love it
  • Hydrates and soothes skin.
  • Convenient and effortless application.
  • Top-notch and luxurious formula.
Main Highlights
  • Skin moisturizer
  • Easy to use
  • Premium quality
Show More
6
Acnecide Face Gel 5% Benzoyl Peroxide Acne Treatment for Spot Prone Skin 15g
Acnecide Face Gel 5% Benzoyl Peroxide Acne Treatment for Spot Prone Skin 15g
Acnecide
25% OffFree Shipping
Why we love it
  • Improves skin with regular use.
  • Reduces bacteria causing acne.
  • Hydrates and soothes skin.
Main Highlights
  • LEAVE-ON MEDICINAL TREATMENT: Treat mild acne or recurring breakouts to help break the cycle of spots; helps unblock pores to reduce blackheads and whiteheads
  • ACTIVE INGREDIENT: Contains 5 percent benzoyl peroxide; clinically proven to target and reduce spot-causing bacteria by up to 95 percent in 1 week
  • EFFECTIVE HYDRATION : Contains "AC Microsphere Technology" which helps absorb excess oil while releasing glycerine to soothe the skin
  • FOR DAILY USE: Apply up to once or twice daily to affected areas after cleansing; avoiding sensitive areas such as the eyes, mouth, nose lining and neck. ALWAYS READ THE LABEL
  • COMPLETE YOUR SKIN-CONFIDENT ROUTINE: Use with Purifide Daily Cleanser and Microbiome Equalizer
Show More
9.4
Superb
9.4
Superb
Acnecide
Acnecide Face Gel 5% Benzoyl Peroxide Acne Treatment for Spot Prone Skin 15g
25% OffFree Shipping
Why we love it
  • Improves skin with regular use.
  • Reduces bacteria causing acne.
  • Hydrates and soothes skin.
Main Highlights
  • LEAVE-ON MEDICINAL TREATMENT: Treat mild acne or recurring breakouts to help break the cycle of spots; helps unblock pores to reduce blackheads and whiteheads
  • ACTIVE INGREDIENT: Contains 5 percent benzoyl peroxide; clinically proven to target and reduce spot-causing bacteria by up to 95 percent in 1 week
  • EFFECTIVE HYDRATION : Contains "AC Microsphere Technology" which helps absorb excess oil while releasing glycerine to soothe the skin
  • FOR DAILY USE: Apply up to once or twice daily to affected areas after cleansing; avoiding sensitive areas such as the eyes, mouth, nose lining and neck. ALWAYS READ THE LABEL
  • COMPLETE YOUR SKIN-CONFIDENT ROUTINE: Use with Purifide Daily Cleanser and Microbiome Equalizer
Show More
7
Nip + Fab Teen Skin Fix Spot Zap Gel for Face with Salicylic Acid, Witch Hazel and Wasabi Extract for Blemish Dark Spot Removal Acne Prevention and Refining Pores
Nip + Fab Teen Skin Fix Spot Zap Gel for Face with Salicylic Acid, Witch Hazel and Wasabi Extract for Blemish Dark Spot Removal Acne Prevention and Refining Pores
Nip+Fab
Free Shipping
Why we love it
  • Minimizes blemishes effectively.
  • Prevents future breakouts.
  • Soothes skin irritation.
Main Highlights
  • MINIMIZE BLEMISHES - Nip + Fab Teen Skin Spot Zap gel for blemishes and spots removal is formulated to help reduce and improve the appearance of blemishes on troubled skin
  • COMBAT ACNE AND BREAKOUTS - Teen Skin Fix Spot Zap Gel for spots deeply penetrates the skin, to refine and minimize the appearance of blemishes, large pores, and prevent future breakouts
  • WITCH HAZEL FOR SKIN - Spot remover gel with witch hazel that helps relieve skin discomfort. Witch hazel products help with acne and in easing skin irritation
  • ANTIOXIDANT WASABI EXTRACT - A powerful antioxidant, this blemish removal gel is formulated with wasabi extract and enriched in eucalyptus + tea tree oils, known for their purifying benefits
  • QUICK AND EASY BALL ROLLER - Gently massage the cooling roller ball directly to the blemish area. Use 2-3 times weekly on sensitive skin, It’s a quick and easy roller ball applicator, the ideal gel for acne-prone skin
Show More
9.2
Superb
9.2
Superb
Nip+Fab
Nip + Fab Teen Skin Fix Spot Zap Gel for Face with Salicylic Acid, Witch Hazel and Wasabi Extract for Blemish Dark Spot Removal Acne Prevention and Refining Pores
Free Shipping
Why we love it
  • Minimizes blemishes effectively.
  • Prevents future breakouts.
  • Soothes skin irritation.
Main Highlights
  • MINIMIZE BLEMISHES - Nip + Fab Teen Skin Spot Zap gel for blemishes and spots removal is formulated to help reduce and improve the appearance of blemishes on troubled skin
  • COMBAT ACNE AND BREAKOUTS - Teen Skin Fix Spot Zap Gel for spots deeply penetrates the skin, to refine and minimize the appearance of blemishes, large pores, and prevent future breakouts
  • WITCH HAZEL FOR SKIN - Spot remover gel with witch hazel that helps relieve skin discomfort. Witch hazel products help with acne and in easing skin irritation
  • ANTIOXIDANT WASABI EXTRACT - A powerful antioxidant, this blemish removal gel is formulated with wasabi extract and enriched in eucalyptus + tea tree oils, known for their purifying benefits
  • QUICK AND EASY BALL ROLLER - Gently massage the cooling roller ball directly to the blemish area. Use 2-3 times weekly on sensitive skin, It’s a quick and easy roller ball applicator, the ideal gel for acne-prone skin
Show More
8
Acnecide Face Wash Gel 5% Benzoyl Peroxide Acne Treatment for Spot-Prone Skin 50g
Acnecide Face Wash Gel 5% Benzoyl Peroxide Acne Treatment for Spot-Prone Skin 50g
Acnecide
25% OffFree Shipping
Why we love it
  • Breaks cycle of spots.
  • Reduces spot-causing bacteria.
  • Soothes and balances skin.
Main Highlights
  • WASH-OFF MEDICINAL TREATMENT: Treat mild acne or recurring breakouts to help break the cycle of spots; helps unblock pores to reduce blackheads and whiteheads
  • EFFECTIVE ACTIVE INGREDIENT: Contains 5% benzoyl peroxide; clinically proven to target and reduce spot-causing bacteria by up to 95%
  • SOOTHING INGREDIENTS: Contains "AC Microsphere Technology" which helps absorb excess oil while releasing glycerine to soothe the skin
  • FOR DAILY USE: Apply up to once or twice daily to cover the affected skin areas; contact time with the skin should be 1 to 2 minutes followed by thorough rinsing with water and drying. ALWAYS READ THE LABEL
  • COMPLETE YOUR SKIN-CONFIDENT ROUTINE: Use with Purifide Daily Cleanser, Purifide Daily Moisturiser SPF30 (for day) & Microbiome Equalizer (for night)
Show More
9.0
Superb
9.0
Superb
Acnecide
Acnecide Face Wash Gel 5% Benzoyl Peroxide Acne Treatment for Spot-Prone Skin 50g
25% OffFree Shipping
Why we love it
  • Breaks cycle of spots.
  • Reduces spot-causing bacteria.
  • Soothes and balances skin.
Main Highlights
  • WASH-OFF MEDICINAL TREATMENT: Treat mild acne or recurring breakouts to help break the cycle of spots; helps unblock pores to reduce blackheads and whiteheads
  • EFFECTIVE ACTIVE INGREDIENT: Contains 5% benzoyl peroxide; clinically proven to target and reduce spot-causing bacteria by up to 95%
  • SOOTHING INGREDIENTS: Contains "AC Microsphere Technology" which helps absorb excess oil while releasing glycerine to soothe the skin
  • FOR DAILY USE: Apply up to once or twice daily to cover the affected skin areas; contact time with the skin should be 1 to 2 minutes followed by thorough rinsing with water and drying. ALWAYS READ THE LABEL
  • COMPLETE YOUR SKIN-CONFIDENT ROUTINE: Use with Purifide Daily Cleanser, Purifide Daily Moisturiser SPF30 (for day) & Microbiome Equalizer (for night)
Show More
9
Dabacc Acne Treatment Cream, 40ml Pimple Cream with S-alicylic acid, Fast Acting Spot Treatment for Face, Spot C/ream Reduces Blemishes & Breakouts, Gentle Skin Care for All Skin Types
Dabacc Acne Treatment Cream, 40ml Pimple Cream with S-alicylic acid, Fast Acting Spot Treatment for Face, Spot C/ream Reduces Blemishes & Breakouts, Gentle Skin Care for All Skin Types
Dabacc
20% OffFree Shipping
Why we love it
  • Effective for all skin types.
  • Quickly soothes irritated skin.
  • Fades acne scars with use.
Main Highlights
  • 【Highly Effective Acne Cream】This pimple cream is a targeted skincare product designed specifically for acne treatment. It quickly reduces acne, alleviates inflammation, and effectively prevents pore blockage. Its formula penetrates deep into the pores to remove dirt and impurities, relieve skin redness and discomfort, and aid in repairing damaged skin, providing a comprehensive acne treatment and repair experience.
  • 【Gentle Soothing Formula】This back acne treatment contains no irritating ingredients and is particularly gentle on sensitive skin. It provides powerful targeted treatment without causing excessive dryness, making it suitable for both daily skincare routines and as a targeted nighttime treatment.
  • 【Fades Acne Scars and Soothes Skin】This acne cream not only combats active acne but also fades post-acne marks, showing significant effects on blackheads, whiteheads, and stubborn blemishes. Additionally, it soothes irritated skin, and long-term use can make the skin texture smoother and more even.
  • 【Lightweight and Non-Greasy】This acne scar cream has a lightweight, easily absorbed texture that leaves no greasy residue or heaviness when applied to the face or body. It quickly forms a protective barrier, providing the skin with essential nutrients for a comfortable and enjoyable skincare experience.
  • 【Multi-functional skincare】This acne cream is suitable for all skin types, including sensitive, oily, and combination skin. It is effective for hormonal acne, skin redness, and blackhead issues, and is suitable for teenagers and adults of all ages.
Show More
8.9
Excellent
8.9
Excellent
Dabacc
Dabacc Acne Treatment Cream, 40ml Pimple Cream with S-alicylic acid, Fast Acting Spot Treatment for Face, Spot C/ream Reduces Blemishes & Breakouts, Gentle Skin Care for All Skin Types
20% OffFree Shipping
Why we love it
  • Effective for all skin types.
  • Quickly soothes irritated skin.
  • Fades acne scars with use.
Main Highlights
  • 【Highly Effective Acne Cream】This pimple cream is a targeted skincare product designed specifically for acne treatment. It quickly reduces acne, alleviates inflammation, and effectively prevents pore blockage. Its formula penetrates deep into the pores to remove dirt and impurities, relieve skin redness and discomfort, and aid in repairing damaged skin, providing a comprehensive acne treatment and repair experience.
  • 【Gentle Soothing Formula】This back acne treatment contains no irritating ingredients and is particularly gentle on sensitive skin. It provides powerful targeted treatment without causing excessive dryness, making it suitable for both daily skincare routines and as a targeted nighttime treatment.
  • 【Fades Acne Scars and Soothes Skin】This acne cream not only combats active acne but also fades post-acne marks, showing significant effects on blackheads, whiteheads, and stubborn blemishes. Additionally, it soothes irritated skin, and long-term use can make the skin texture smoother and more even.
  • 【Lightweight and Non-Greasy】This acne scar cream has a lightweight, easily absorbed texture that leaves no greasy residue or heaviness when applied to the face or body. It quickly forms a protective barrier, providing the skin with essential nutrients for a comfortable and enjoyable skincare experience.
  • 【Multi-functional skincare】This acne cream is suitable for all skin types, including sensitive, oily, and combination skin. It is effective for hormonal acne, skin redness, and blackhead issues, and is suitable for teenagers and adults of all ages.
Show More
10
Avon clear skin spot on instant gel
Avon clear skin spot on instant gel
Avon
Free Shipping
8.8
Excellent
8.8
Excellent
Avon
Avon clear skin spot on instant gel
Free Shipping