Best Topical Treatments of 2025

Last updated on 22/09/2025
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1
The 2023 Report on Topical Stretch Marks Treatment Products: World Market Segmentation by City
The 2023 Report on Topical Stretch Marks Treatment Products: World Market Segmentation by City
ICON Group International, Inc.
Free Shipping
9.8
Exceptional
9.8
Exceptional
ICON Group International, Inc.
The 2023 Report on Topical Stretch Marks Treatment Products: World Market Segmentation by City
Free Shipping
Value for Money
2
The 2023 Report on Topical Atrophic Scar Treatment Products: World Market Segmentation by City
The 2023 Report on Topical Atrophic Scar Treatment Products: World Market Segmentation by City
ICON Group International, Inc.
Free Shipping
9.6
Superb
9.6
Superb
ICON Group International, Inc.
The 2023 Report on Topical Atrophic Scar Treatment Products: World Market Segmentation by City
Free Shipping
3
The 2023 Report on Topical Drugs for Hyperpigmentation Disorders Treatments: World Market Segmentation by City
The 2023 Report on Topical Drugs for Hyperpigmentation Disorders Treatments: World Market Segmentation by City
ICON Group International, Inc.
Free Shipping
9.6
Superb
9.6
Superb
ICON Group International, Inc.
The 2023 Report on Topical Drugs for Hyperpigmentation Disorders Treatments: World Market Segmentation by City
Free Shipping
4
The 2023-2028 Outlook for Topical Scar Treatment Products in China
The 2023-2028 Outlook for Topical Scar Treatment Products in China
ICON Group International, Inc.
Free Shipping
9.5
Superb
9.5
Superb
ICON Group International, Inc.
The 2023-2028 Outlook for Topical Scar Treatment Products in China
Free Shipping
5
E45 Psoriasis Cream 50 ml – Treatment for Psoriasis Symptoms – to Reduce Scaling, Itching, Redness, Roughness, Dry, Hard Skin – Moisturising E45 Cream – Relieve Irritated Skin
E45 Psoriasis Cream 50 ml – Treatment for Psoriasis Symptoms – to Reduce Scaling, Itching, Redness, Roughness, Dry, Hard Skin – Moisturising E45 Cream – Relieve Irritated Skin
E45
31% OffFree Shipping
Why we love it
  • Eases psoriasis and dermatitis symptoms.
  • Reduces inflammation effectively.
  • Stabilises and regenerates skin.
Main Highlights
  • TREAT SYMPTOMS OF PSORIASIS – E45 Psoriasis Cream has been formulated to treat and prevent psoriasis and dermatitis symptoms and has been scientifically proven to reduce scaling itching, redness, roughness and hardening of the skin. The moisturising cream is full of nourishing ingredients that hydrate and stabilise the skin’s barrier, as well as supporting the skin’s natural regeneration process. It helps with dry, itchy, red, flaky skin and reduces roughness and hardening of psoriasis plaques.
  • WHAT IS PSORIASIS? – Psoriasis is a long-lasting skin condition which causes flaky patches of skin which form scales. These patches can appear anywhere on the body but most commonly the elbows, knees, scalp, and lower back. They can look pink or red and the scales white or silvery, and on darker skin the patches can look purple or dark brown with grey scales. The patches can be sore and itchy. E45 Psoriasis Cream is intended for the treatment and prevention of psoriasis and dermatitis symptoms.
  • REDUCE INFLAMMATION - E45 Psoriasis Cream contains Ectoin, a natural cell-protective molecule with inflammation-reducing and membrane-stabilising properties. Our Cream relieves and calms irritated and damaged skin by reducing inflammatory reactions and supporting the regeneration process of the skin. This cream is suitable for long term use and is a steroid-free psoriasis treatment. It should be gently massaged into the affected areas of skin 3 times a day or as often as needed.
  • QUALITY SKINCARE EVERY DAY – For 60 years, E45 has been a skincare expert in dry and itchy skin and treatment for eczema, psoriasis, ichthyosis and other dry skin conditions. We understand the importance of quality everyday products that care for your skin with minimal fuss. The E45 range of products has been developed for different skin types and parts of the body and works hard to protect and maintain skin health. It has proven dermatological expertise dedicated to vulnerable dry skin.
  • HISTORY OF E45 – We released our E45 Cream in 1952 after a customer request for a product that would soothe and protect the skin. In 1963 physicians noticed the benefits of E45 cream for dry skin conditions and our cream was introduced to pharmacy and retail in 1980. We’ve continued to create products with patients and their skin in mind. We strive to continue to serve the needs of patients and healthcare professionals and produce better treatment options for patients' skincare routines.
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9.5
Superb
9.5
Superb
E45
E45 Psoriasis Cream 50 ml – Treatment for Psoriasis Symptoms – to Reduce Scaling, Itching, Redness, Roughness, Dry, Hard Skin – Moisturising E45 Cream – Relieve Irritated Skin
31% OffFree Shipping
Why we love it
  • Eases psoriasis and dermatitis symptoms.
  • Reduces inflammation effectively.
  • Stabilises and regenerates skin.
Main Highlights
  • TREAT SYMPTOMS OF PSORIASIS – E45 Psoriasis Cream has been formulated to treat and prevent psoriasis and dermatitis symptoms and has been scientifically proven to reduce scaling itching, redness, roughness and hardening of the skin. The moisturising cream is full of nourishing ingredients that hydrate and stabilise the skin’s barrier, as well as supporting the skin’s natural regeneration process. It helps with dry, itchy, red, flaky skin and reduces roughness and hardening of psoriasis plaques.
  • WHAT IS PSORIASIS? – Psoriasis is a long-lasting skin condition which causes flaky patches of skin which form scales. These patches can appear anywhere on the body but most commonly the elbows, knees, scalp, and lower back. They can look pink or red and the scales white or silvery, and on darker skin the patches can look purple or dark brown with grey scales. The patches can be sore and itchy. E45 Psoriasis Cream is intended for the treatment and prevention of psoriasis and dermatitis symptoms.
  • REDUCE INFLAMMATION - E45 Psoriasis Cream contains Ectoin, a natural cell-protective molecule with inflammation-reducing and membrane-stabilising properties. Our Cream relieves and calms irritated and damaged skin by reducing inflammatory reactions and supporting the regeneration process of the skin. This cream is suitable for long term use and is a steroid-free psoriasis treatment. It should be gently massaged into the affected areas of skin 3 times a day or as often as needed.
  • QUALITY SKINCARE EVERY DAY – For 60 years, E45 has been a skincare expert in dry and itchy skin and treatment for eczema, psoriasis, ichthyosis and other dry skin conditions. We understand the importance of quality everyday products that care for your skin with minimal fuss. The E45 range of products has been developed for different skin types and parts of the body and works hard to protect and maintain skin health. It has proven dermatological expertise dedicated to vulnerable dry skin.
  • HISTORY OF E45 – We released our E45 Cream in 1952 after a customer request for a product that would soothe and protect the skin. In 1963 physicians noticed the benefits of E45 cream for dry skin conditions and our cream was introduced to pharmacy and retail in 1980. We’ve continued to create products with patients and their skin in mind. We strive to continue to serve the needs of patients and healthcare professionals and produce better treatment options for patients' skincare routines.
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6
Topical Treatment Kit - Kusuri 8 Piece Kit
Topical Treatment Kit - Kusuri 8 Piece Kit
Kusuri
Main Highlights
  • A complete easy to use kit, for the beginner or experienced fish keeper. For treating Ulcers, wounds and Fin Rot All kit components are replaceable, so you need never run short of any particular item.
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9.3
Superb
9.3
Superb
Kusuri
Topical Treatment Kit - Kusuri 8 Piece Kit
Main Highlights
  • A complete easy to use kit, for the beginner or experienced fish keeper. For treating Ulcers, wounds and Fin Rot All kit components are replaceable, so you need never run short of any particular item.
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7
Acnecide Face Gel 5% Benzoyl Peroxide Acne Treatment for Spot Prone Skin 15g
Acnecide Face Gel 5% Benzoyl Peroxide Acne Treatment for Spot Prone Skin 15g
Acnecide
25% OffFree Shipping
Why we love it
  • Improves skin with regular use.
  • Reduces bacteria causing acne.
  • Hydrates and soothes skin.
Main Highlights
  • LEAVE-ON MEDICINAL TREATMENT: Treat mild acne or recurring breakouts to help break the cycle of spots; helps unblock pores to reduce blackheads and whiteheads
  • ACTIVE INGREDIENT: Contains 5 percent benzoyl peroxide; clinically proven to target and reduce spot-causing bacteria by up to 95 percent in 1 week
  • EFFECTIVE HYDRATION : Contains "AC Microsphere Technology" which helps absorb excess oil while releasing glycerine to soothe the skin
  • FOR DAILY USE: Apply up to once or twice daily to affected areas after cleansing; avoiding sensitive areas such as the eyes, mouth, nose lining and neck. ALWAYS READ THE LABEL
  • COMPLETE YOUR SKIN-CONFIDENT ROUTINE: Use with Purifide Daily Cleanser and Microbiome Equalizer
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9.2
Superb
9.2
Superb
Acnecide
Acnecide Face Gel 5% Benzoyl Peroxide Acne Treatment for Spot Prone Skin 15g
25% OffFree Shipping
Why we love it
  • Improves skin with regular use.
  • Reduces bacteria causing acne.
  • Hydrates and soothes skin.
Main Highlights
  • LEAVE-ON MEDICINAL TREATMENT: Treat mild acne or recurring breakouts to help break the cycle of spots; helps unblock pores to reduce blackheads and whiteheads
  • ACTIVE INGREDIENT: Contains 5 percent benzoyl peroxide; clinically proven to target and reduce spot-causing bacteria by up to 95 percent in 1 week
  • EFFECTIVE HYDRATION : Contains "AC Microsphere Technology" which helps absorb excess oil while releasing glycerine to soothe the skin
  • FOR DAILY USE: Apply up to once or twice daily to affected areas after cleansing; avoiding sensitive areas such as the eyes, mouth, nose lining and neck. ALWAYS READ THE LABEL
  • COMPLETE YOUR SKIN-CONFIDENT ROUTINE: Use with Purifide Daily Cleanser and Microbiome Equalizer
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8
Fenistil Gel 30g Insect Bites -, Skin Allergies, Sunburn, and Dermatitis Itch Treatment – Fast-Acting Topical Antihistamine Gel for Itchy, Irritated, or Inflamed Skin
Fenistil Gel 30g Insect Bites -, Skin Allergies, Sunburn, and Dermatitis Itch Treatment – Fast-Acting Topical Antihistamine Gel for Itchy, Irritated, or Inflamed Skin
Makro Space
Free Shipping
Why we love it
  • Immediate relief from itching.
  • Cooling, non-greasy application.
  • Safe for all ages.
Main Highlights
  • Immediate and Long-Lasting Relief from Itching and Skin Irritation: Fenistil Gel offers rapid and effective relief from itching caused by insect bites, allergic skin reactions, hives (urticaria), and mild eczema. The advanced antihistamine formula starts working within minutes of application, blocking the histamines that cause skin discomfort.
  • Cooling and Soothing Gel Formula That Absorbs Quickly: This fast-absorbing gel provides a refreshing cooling sensation on the skin, helping to calm irritated areas without leaving behind a greasy or sticky residue. Ideal for hot summer days, bug bites, or sun exposure.
  • Clinically Proven Antihistamine Ingredient – Dimetindene Maleate: Formulated with Dimetindene Maleate, a clinically effective topical antihistamine, Fenistil helps reduce redness, swelling, and itching at the source. Works by targeting the histamine receptors in the skin to relieve inflammation and allergic symptoms.
  • Multi-Purpose Use for Everyday Skin Emergencies at Home or On the Go: Perfect for treating a wide range of skin irritations, including sunburn, contact dermatitis, mild eczema, insect bites, and minor allergic reactions. Its compact 30g size makes it a must-have in your travel bag, handbag, or first aid kit.
  • Safe for Adults and Children Over 1 Year – Dermatologically Tested: Gentle enough for daily use and suitable for adults and children over the age of 1. Dermatologically tested for skin tolerance. Always read the leaflet and consult a healthcare professional if using on young children or sensitive skin.
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9.1
Superb
9.1
Superb
Makro Space
Fenistil Gel 30g Insect Bites -, Skin Allergies, Sunburn, and Dermatitis Itch Treatment – Fast-Acting Topical Antihistamine Gel for Itchy, Irritated, or Inflamed Skin
Free Shipping
Why we love it
  • Immediate relief from itching.
  • Cooling, non-greasy application.
  • Safe for all ages.
Main Highlights
  • Immediate and Long-Lasting Relief from Itching and Skin Irritation: Fenistil Gel offers rapid and effective relief from itching caused by insect bites, allergic skin reactions, hives (urticaria), and mild eczema. The advanced antihistamine formula starts working within minutes of application, blocking the histamines that cause skin discomfort.
  • Cooling and Soothing Gel Formula That Absorbs Quickly: This fast-absorbing gel provides a refreshing cooling sensation on the skin, helping to calm irritated areas without leaving behind a greasy or sticky residue. Ideal for hot summer days, bug bites, or sun exposure.
  • Clinically Proven Antihistamine Ingredient – Dimetindene Maleate: Formulated with Dimetindene Maleate, a clinically effective topical antihistamine, Fenistil helps reduce redness, swelling, and itching at the source. Works by targeting the histamine receptors in the skin to relieve inflammation and allergic symptoms.
  • Multi-Purpose Use for Everyday Skin Emergencies at Home or On the Go: Perfect for treating a wide range of skin irritations, including sunburn, contact dermatitis, mild eczema, insect bites, and minor allergic reactions. Its compact 30g size makes it a must-have in your travel bag, handbag, or first aid kit.
  • Safe for Adults and Children Over 1 Year – Dermatologically Tested: Gentle enough for daily use and suitable for adults and children over the age of 1. Dermatologically tested for skin tolerance. Always read the leaflet and consult a healthcare professional if using on young children or sensitive skin.
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9
E45 Itch Relief Coolmousse 100ml – Face and Body Foam for Dry Skin, Itchy Skin and Irritated Skin - Cooling Foam to Soothe Itchy Skin
E45 Itch Relief Coolmousse 100ml – Face and Body Foam for Dry Skin, Itchy Skin and Irritated Skin - Cooling Foam to Soothe Itchy Skin
E45
Free Shipping
Why we love it
  • Soothes itchy skin quickly.
  • Proven skincare expertise.
  • Suitable for family use.
Main Highlights
  • QUALITY SKINCARE EVERY DAY – For 60 years, E45 has been a skincare expert in dry and itchy skin and treatment for eczema, psoriasis, ichthyosis and other dry skin conditions. We understand the importance of quality everyday products that care for your skin with minimal fuss. The E45 range of products has been developed for different skin types and parts of the body and works hard to protect and maintain skin health. It has proven dermatological expertise dedicated to vulnerable dry skin.
  • DUAL ACTION - E45 Itch Relief Coolmousse instantly cools and soothes dry, itchy and irritated skin. Formulated with Betaine, a natural osmoprotectant with moisturising and calming properties, and highly purified Aloe Vera leaf extract to soothe and hydrate.
  • FAST ABSORBING - Lightweight foam texture, easily absorbed without leaving sticky residue for immediate, soothing relief.
  • HOW TO USE – E45 Itch Relief Coolmousse is perfume-free and suitable for dry, itchy and irritated skin. Suitable to use on body, face and hands and safe for the whole family. Simply shake the can 1-2 times before use, press foam into palm and apply softly to the affected skin area without rubbing. Use as frequently as needed. For added cooling relief, store in the fridge. For additional moisturisation, use in conjunction with an emollient.
  • HISTORY OF E45 – We released our E45 Cream in 1952 after a customer request for a product that would soothe and protect the skin. In 1963 physicians noticed the benefits of E45 cream for dry skin conditions and our cream was introduced to pharmacy and retail in 1980. We’ve continued to create products with patients and their skin in mind. We strive to continue to serve the needs of patients and healthcare professionals and produce better treatment options for patients' skincare routines.
Show More
9.0
Superb
9.0
Superb
E45
E45 Itch Relief Coolmousse 100ml – Face and Body Foam for Dry Skin, Itchy Skin and Irritated Skin - Cooling Foam to Soothe Itchy Skin
Free Shipping
Why we love it
  • Soothes itchy skin quickly.
  • Proven skincare expertise.
  • Suitable for family use.
Main Highlights
  • QUALITY SKINCARE EVERY DAY – For 60 years, E45 has been a skincare expert in dry and itchy skin and treatment for eczema, psoriasis, ichthyosis and other dry skin conditions. We understand the importance of quality everyday products that care for your skin with minimal fuss. The E45 range of products has been developed for different skin types and parts of the body and works hard to protect and maintain skin health. It has proven dermatological expertise dedicated to vulnerable dry skin.
  • DUAL ACTION - E45 Itch Relief Coolmousse instantly cools and soothes dry, itchy and irritated skin. Formulated with Betaine, a natural osmoprotectant with moisturising and calming properties, and highly purified Aloe Vera leaf extract to soothe and hydrate.
  • FAST ABSORBING - Lightweight foam texture, easily absorbed without leaving sticky residue for immediate, soothing relief.
  • HOW TO USE – E45 Itch Relief Coolmousse is perfume-free and suitable for dry, itchy and irritated skin. Suitable to use on body, face and hands and safe for the whole family. Simply shake the can 1-2 times before use, press foam into palm and apply softly to the affected skin area without rubbing. Use as frequently as needed. For added cooling relief, store in the fridge. For additional moisturisation, use in conjunction with an emollient.
  • HISTORY OF E45 – We released our E45 Cream in 1952 after a customer request for a product that would soothe and protect the skin. In 1963 physicians noticed the benefits of E45 cream for dry skin conditions and our cream was introduced to pharmacy and retail in 1980. We’ve continued to create products with patients and their skin in mind. We strive to continue to serve the needs of patients and healthcare professionals and produce better treatment options for patients' skincare routines.
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10
Sons Minoxidil 5% Cutaneous Solution for Men, Hair Regrowth & Thickener Formula, For Hair Loss & Thinning, Reactivates Shrunken Follicles, Precision Application System, 3 Month Supply Made in Europe
Sons Minoxidil 5% Cutaneous Solution for Men, Hair Regrowth & Thickener Formula, For Hair Loss & Thinning, Reactivates Shrunken Follicles, Precision Application System, 3 Month Supply Made in Europe
Sons
Free Shipping
Why we love it
  • Easy-to-use pump dispenser.
  • FDA-approved for hair loss.
  • Visible results in 90 days.
Main Highlights
  • WHAT IS MINOXIDIL? Two-thirds of men will experience some hair loss before 35. Sons Minoxidil is a clinically proven treatment for male pattern hair loss that improves scalp blood flow and reactivates shrinking follicles.
  • HOW DO I USE IT? Spray 1ml (10 pumps) twice daily on a dry scalp - morning and night. Spread with fingertips over thinning areas, then wash hands.
  • WHY CHOOSE SONS MINOXIDIL SPRAY? Trusted by 300,000+ men, Sons is the UK license holder for the only two clinically proven hair loss treatments. The precision nozzle targets hair loss at the root.
  • HOW EFFECTIVE IS IT? Clinically proven to stop hair loss in 84% of men, with first visible results after 90 days of consistent use.
  • WHAT IS INCLUDED? 3x 60ml Minoxidil 5% solution with pump dispenser for targeted application.
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8.8
Excellent
8.8
Excellent
Sons
Sons Minoxidil 5% Cutaneous Solution for Men, Hair Regrowth & Thickener Formula, For Hair Loss & Thinning, Reactivates Shrunken Follicles, Precision Application System, 3 Month Supply Made in Europe
Free Shipping
Why we love it
  • Easy-to-use pump dispenser.
  • FDA-approved for hair loss.
  • Visible results in 90 days.
Main Highlights
  • WHAT IS MINOXIDIL? Two-thirds of men will experience some hair loss before 35. Sons Minoxidil is a clinically proven treatment for male pattern hair loss that improves scalp blood flow and reactivates shrinking follicles.
  • HOW DO I USE IT? Spray 1ml (10 pumps) twice daily on a dry scalp - morning and night. Spread with fingertips over thinning areas, then wash hands.
  • WHY CHOOSE SONS MINOXIDIL SPRAY? Trusted by 300,000+ men, Sons is the UK license holder for the only two clinically proven hair loss treatments. The precision nozzle targets hair loss at the root.
  • HOW EFFECTIVE IS IT? Clinically proven to stop hair loss in 84% of men, with first visible results after 90 days of consistent use.
  • WHAT IS INCLUDED? 3x 60ml Minoxidil 5% solution with pump dispenser for targeted application.
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